The Swiss cohort of elderly patients with venous thromboembolism (SWITCO65+): rationale and methodology
Méan, Marie ; Righini, Marc ; Jaeger, Kurt ; Beer, Hans-Jürg ; Frauchiger, Beat ; Osterwalder, Joseph ; Kucher, Nils ; Lämmle, Bernhard ; Cornuz, Jacques ; Angelillo-Scherrer, Anne ; Rodondi, Nicolas ; Limacher, Andreas ; Trelle, Sven ; Matter, Christian ; Husmann, Marc ; Banyai, Martin ; Aschwanden, Markus ; Egloff, Michael ; Mazzolai, Lucia ; Hugli, Olivier ; Bounameaux, Henri ; Aujesky, Drahomir
In: Journal of Thrombosis and Thrombolysis, 2013, vol. 36, no. 4, p. 475-483
Ajouter à la liste personnelle- Summary
- Venous thromboembolism (VTE) is common and has a high impact on morbidity, mortality, and costs of care. Although most of the patients with VTE are aged ≥65years, there is little data about the medical outcomes in the elderly with VTE. The Swiss Cohort of Elderly Patients with VTE (SWITCO65+) is a prospective multicenter cohort study of in- and outpatients aged ≥65years with acute VTE from all five Swiss university and four high-volume non-university hospitals. The goal is to examine which clinical and biological factors and processes of care drive short- and long-term medical outcomes, health-related quality of life, and medical resource utilization in elderly patients with acute VTE. The cohort also includes a large biobank with biological material from each participant. From September 2009 to March 2012, 1,863 elderly patients with VTE were screened and 1003 (53.8%) were enrolled in the cohort. Overall, 51.7% of patients were aged ≥75years and 52.7% were men. By October 16, 2012, after an average follow-up time of 512days, 799 (79.7%) patients were still actively participating. SWITCO65+ is a unique opportunity to study short- and long-term outcomes in elderly patients with VTE. The Steering Committee encourages national and international collaborative research projects related to SWITCO65+, including sharing anonymized data and biological samples