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The Swiss cohort of elderly patients with venous thromboembolism (SWITCO65+): rationale and methodology

Méan, Marie ; Righini, Marc ; Jaeger, Kurt ; Beer, Hans-Jürg ; Frauchiger, Beat ; Osterwalder, Joseph ; Kucher, Nils ; Lämmle, Bernhard ; Cornuz, Jacques ; Angelillo-Scherrer, Anne ; Rodondi, Nicolas ; Limacher, Andreas ; Trelle, Sven ; Matter, Christian ; Husmann, Marc ; Banyai, Martin ; Aschwanden, Markus ; Egloff, Michael ; Mazzolai, Lucia ; Hugli, Olivier ; Bounameaux, Henri ; Aujesky, Drahomir

In: Journal of Thrombosis and Thrombolysis, 2013, vol. 36, no. 4, p. 475-483

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    Titre
    • The Swiss cohort of elderly patients with venous thromboembolism (SWITCO65+): rationale and methodology
    Auteur
    • Méan, Marie. Division of General Internal Medicine, Bern University Hospital, Inselspital, 3010, Bern, Switzerland
    • Righini, Marc. Division of Angiology and Hemostasis, Geneva University Hospital, Geneva, Switzerland
    • Jaeger, Kurt. Department of Angiology, Basel University Hospital, Basel, Switzerland
    • Beer, Hans-Jürg. Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland
    • Frauchiger, Beat. Department of Internal Medicine, Cantonal Hospital of Frauenfeld, Frauenfeld, Switzerland
    • Osterwalder, Joseph. Emergency Department, Cantonal Hospital of St. Gallen, St. Gallen, Switzerland
    • Kucher, Nils. Division of Angiology, Bern University Hospital, Bern, Switzerland
    • Lämmle, Bernhard. Division of Hematology and Central Hematology Laboratory, Bern University Hospital, Bern, Switzerland
    • Cornuz, Jacques. Department of Ambulatory Care and Community Medicine, Policlinique Médicale Universitaire, Lausanne, Switzerland
    • Angelillo-Scherrer, Anne. Service and Central Laboratory of Hematology, Lausanne University Hospital, Lausanne, Switzerland
    • Rodondi, Nicolas. Division of General Internal Medicine, Bern University Hospital, Inselspital, 3010, Bern, Switzerland
    • Limacher, Andreas. Clinical Trials Unit, University of Bern, Bern, Switzerland
    • Trelle, Sven. Clinical Trials Unit, University of Bern, Bern, Switzerland
    • Matter, Christian. Cardiovascular Research, Institute of Physiology, Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland
    • Husmann, Marc. Division of Angiology, Zurich University Hospital, Zurich, Switzerland
    • Banyai, Martin. Division of Angiology, Cantonal Hospital of Lucerne, Lucerne, Switzerland
    • Aschwanden, Markus. Department of Angiology, Basel University Hospital, Basel, Switzerland
    • Egloff, Michael. Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland
    • Mazzolai, Lucia. Service of Angiology, Lausanne University Hospital, Lausanne, Switzerland
    • Hugli, Olivier. Emergency Department, Lausanne University Hospital, Lausanne, Switzerland
    • Bounameaux, Henri. Division of Angiology and Hemostasis, Geneva University Hospital, Geneva, Switzerland
    • Aujesky, Drahomir. Division of General Internal Medicine, Bern University Hospital, Inselspital, 3010, Bern, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • Journal of Thrombosis and Thrombolysis, 2013, vol. 36, no. 4, p. 475-483. Springer US; http://www.springer-ny.com
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:313273
    Summary
    Venous thromboembolism (VTE) is common and has a high impact on morbidity, mortality, and costs of care. Although most of the patients with VTE are aged ≥65years, there is little data about the medical outcomes in the elderly with VTE. The Swiss Cohort of Elderly Patients with VTE (SWITCO65+) is a prospective multicenter cohort study of in- and outpatients aged ≥65years with acute VTE from all five Swiss university and four high-volume non-university hospitals. The goal is to examine which clinical and biological factors and processes of care drive short- and long-term medical outcomes, health-related quality of life, and medical resource utilization in elderly patients with acute VTE. The cohort also includes a large biobank with biological material from each participant. From September 2009 to March 2012, 1,863 elderly patients with VTE were screened and 1003 (53.8%) were enrolled in the cohort. Overall, 51.7% of patients were aged ≥75years and 52.7% were men. By October 16, 2012, after an average follow-up time of 512days, 799 (79.7%) patients were still actively participating. SWITCO65+ is a unique opportunity to study short- and long-term outcomes in elderly patients with VTE. The Steering Committee encourages national and international collaborative research projects related to SWITCO65+, including sharing anonymized data and biological samples