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Normalizing effect of heroin maintenance treatment on stress-induced brain connectivity

Schmidt, André ; Walter, Marc ; Gerber, Hana ; Seifritz, Erich ; Brenneisen, Rudolf ; Wiesbeck, Gerhard A. ; Riecher-Rössler, Anita ; Lang, Undine E. ; Borgwardt, Stefan

In: Brain, 2015, vol. 138, no. 1, p. 217-228

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    Titre
    • Normalizing effect of heroin maintenance treatment on stress-induced brain connectivity
    Auteur
    • Schmidt, André. 1 Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012 Basel, Switzerland
    • Walter, Marc. 1 Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012 Basel, Switzerland
    • Gerber, Hana. 1 Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012 Basel, Switzerland
    • Seifritz, Erich. 4 Department of Psychiatry, Psychotherapy and Psychosomatics, Hospital of Psychiatry, University of Zurich, 8032 Zurich, Switzerland
    • Brenneisen, Rudolf. 5 Department of Clinical Research (DCR), University of Bern, 3010 Bern, Switzerland
    • Wiesbeck, Gerhard A.. 1 Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012 Basel, Switzerland
    • Riecher-Rössler, Anita. 1 Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012 Basel, Switzerland
    • Lang, Undine E.. 1 Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012 Basel, Switzerland
    • Borgwardt, Stefan. 1 Department of Psychiatry (UPK), University of Basel, Wilhelm Klein-Strasse 27, 4012 Basel, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Brain, 2015, vol. 138, no. 1, p. 217-228. Oxford University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:301488
    Summary
    A single dose of heroin can reduce stress responses in heroin-dependent patients. Schmidt et al. report that increased amygdala-related functional connectivity during fearful face processing in heroin-dependent patients transiently normalises after a single dose of heroin. This measure may help to assess the efficacy of maintenance treatments in drug addiction