Normalizing effect of heroin maintenance treatment on stress-induced brain connectivity
Schmidt, André ; Walter, Marc ; Gerber, Hana ; Seifritz, Erich ; Brenneisen, Rudolf ; Wiesbeck, Gerhard A. ; Riecher-Rössler, Anita ; Lang, Undine E. ; Borgwardt, Stefan
In: Brain, 2015, vol. 138, no. 1, p. 217-228
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- A single dose of heroin can reduce stress responses in heroin-dependent patients. Schmidt et al. report that increased amygdala-related functional connectivity during fearful face processing in heroin-dependent patients transiently normalises after a single dose of heroin. This measure may help to assess the efficacy of maintenance treatments in drug addiction