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Predictors for Improvement of Problem-Solving during Cognitive Remediation for Patients with Schizophrenia

Rodewald, Katlehn ; Holt, Daniel V. ; Rentrop, Mirjam ; Roesch-Ely, Daniela ; Liebrenz, Michael ; Funke, Joachim ; Weisbrod, Matthias ; Kaiser, Stefan

In: Journal of the International Neuropsychological Society, 2014, vol. 20, no. 4, p. 455-460

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    Titre
    • Predictors for Improvement of Problem-Solving during Cognitive Remediation for Patients with Schizophrenia
    Auteur
    • Rodewald, Katlehn. Section of Experimental Psychopathology and Neurophysiology, Department of General Adult Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany
    • Holt, Daniel V.. Department of Psychology, University of Heidelberg, Heidelberg, Germany
    • Rentrop, Mirjam. Section of Experimental Psychopathology and Neurophysiology, Department of General Adult Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany
    • Roesch-Ely, Daniela. Section of Experimental Psychopathology and Neurophysiology, Department of General Adult Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany
    • Liebrenz, Michael. Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland
    • Funke, Joachim. Department of Psychology, University of Heidelberg, Heidelberg, Germany
    • Weisbrod, Matthias. Section of Experimental Psychopathology and Neurophysiology, Department of General Adult Psychiatry, Centre for Psychosocial Medicine, University of Heidelberg, Heidelberg, Germany
    • Kaiser, Stefan. Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • Journal of the International Neuropsychological Society, 2014, vol. 20, no. 4, p. 455-460. Cambridge University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:298096
    Summary
    Cognitive remediation is a promising pathway for ameliorating cognitive impairment of patients with schizophrenia. Here, we investigate predictors of improvement in problem-solving ability for two different types of cognitive remediation - specific problem-solving training and training of basic cognition. For this purpose we conducted a re-analysis of a randomized controlled trial comparing these two training approaches. The main outcome measure was improvement in problem-solving performance. Correlational analyses were used to assess the contribution of clinical, cognitive and training-related predictors. In the problem-solving training group, impaired pre-training planning ability was associated with stronger improvement. In contrast, in the basic cognition training group antipsychotic medication dose emerged as a negative predictor. These results demonstrate that predictors for successful cognitive remediation depend on the specific intervention. Furthermore, our results suggest that at least in the planning domain patients with impaired performance benefit particularly from a specific intervention. (JINS, 2014, 20, 1-6)