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Tract-based spatial statistics to assess the neuroprotective effect of early erythropoietin on white matter development in preterm infants

O'Gorman, Ruth L. ; Bucher, Hans U. ; Held, Ulrike ; Koller, Brigitte M. ; Hüppi, Petra S. ; Hagmann, Cornelia F.

In: Brain, 2015, vol. 138, no. 2, p. 388-397

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    Titre
    • Tract-based spatial statistics to assess the neuroprotective effect of early erythropoietin on white matter development in preterm infants
    Auteur
    • O'Gorman, Ruth L.. 1 MR Research Centre, Children's University Hospital of Zurich, Switzerland
    • Bucher, Hans U.. 2 Department of Neonatology, University Hospital of Zurich, Switzerland
    • Held, Ulrike. 3 Horten Centre, University Hospital of Zurich, Switzerland
    • Koller, Brigitte M.. 2 Department of Neonatology, University Hospital of Zurich, Switzerland
    • Hüppi, Petra S.. 3 Horten Centre, University Hospital of Zurich, Switzerland
    • Hagmann, Cornelia F.. 2 Department of Neonatology, University Hospital of Zurich, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Brain, 2015, vol. 138, no. 2, p. 388-397. Oxford University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:296623
    Summary
    In a randomized double-blind placebo-controlled trial, O'Gorman et al. show that administration of erythropoietin within the first 42 hours after preterm birth improves white matter development in preterm infants. Improvements are seen in the corpus callosum, the anterior and posterior limbs of the internal capsule, and the corticospinal tract bilaterally