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Ubiquitin-specific protease USP2-45 acts as a molecular switch to promote α2δ-1-induced downregulation of Cav1.2 channels

Rougier, Jean-Sebastien ; Albesa, Maxime ; Syam, Ninda ; Halet, Guillaume ; Abriel, Hugues ; Viard, Patricia

In: Pflügers Archiv - European Journal of Physiology, 2015, vol. 467, no. 9, p. 1919-1929

Role of connexins and pannexins in cardiovascular physiology

Meens, Merlijn ; Kwak, Brenda ; Duffy, Heather

In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 15, p. 2779-2792

The lung communication network

Losa, Davide ; Chanson, Marc

In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 15, p. 2793-2808

Tissue-specific isoforms of the single C. elegans Ryanodine receptor gene unc-68 control specific functions

Marques, Filipe ; Thapliyal, Saurabh ; Javer, Avelino ; Shrestha, Priyanka ; Brown, André E. X. ; Glauser, Dominique A.

In: PLOS Genetics, 2020, vol. 16, no. 10, p. e1009102

Ryanodine receptors (RyR) are essential regulators of cellular calcium homeostasis and signaling. Vertebrate genomes contain multiple RyR gene isoforms, expressed in different tissues and executing different functions. In contrast, invertebrate genomes contain a single RyR-encoding gene and it has long been proposed that different transcripts generated by alternative splicing may diversify...

Specific ion channels control sensory gain, sensitivity, and kinetics in a tonic thermonociceptor

Saro, Gabriella ; Lia, Andrei-Stefan ; Thapliyal, Saurabh ; Marques, Filipe ; Busch, Karl Emanuel ; Glauser, Dominique A.

In: Cell Reports, 2020, vol. 30, no. 2, p. 397-408.e4

Pain sensation and aversive behaviors entail the activation of nociceptor neurons, whose function is largely conserved across animals. The functional heterogeneity of nociceptors and ethical concerns are challenges for their study in mammalian models. Here, we investigate the function of a single type of genetically identified C. elegans thermonociceptor named FLP. Using calcium imaging in...

Presynaptic K+ Channels, Vesicular Ca2+/H+ Antiport—Synaptotagmin, and Acetylcholinesterase, Three Mechanisms Cutting Short the Cholinergic Signal at Neuromuscular and Nerve-Electroplaque Junctions

Dunant, Yves ; Cordeiro, J.

In: Journal of Molecular Neuroscience, 2014, vol. 53, no. 3, p. 377-386

Pitfalls when examining gap junction hemichannels: interference from volume-regulated anion channels

Bader, Patrick ; Weingart, Robert

In: Pflügers Archiv, 2006, vol. 452, no. 4, p. 396-406

The electrical behaviour of rat connexin46 gap junction channels expressed in transfected HeLa cells

Sakai, Rieko ; Elfgang, Claudia ; Vogel, Rolf ; Willecke, Klaus ; Weingart, Robert

In: Pflügers Archiv, 2003, vol. 446, no. 6, p. 714-727

Ascending aorta measurements as assessed by ECG-gated multi-detector computed tomography: a pilot study to establish normative values for transcatheter therapies

Lu, Tri-Linh ; Huber, Christoph ; Rizzo, Elena ; Dehmeshki, Jashmid ; von Segesser, Ludwig ; Qanadli, Salah

In: European Radiology, 2009, vol. 19, no. 3, p. 664-669

Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding

Scheib, Holger ; McLay, Iain ; Guex, Nicolas ; Clare, Jeff ; Blaney, Frank ; Dale, Tim ; Tate, Simon ; Robertson, Graeme

In: Journal of Molecular Modeling, 2006, vol. 12, no. 6, p. 813-822