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Dexamethasone induces changes in osteogenic differentiation of human mesenchymal stromal cells via SOX9 and PPARG, but not RUNX2

Della Bella, Elena ; Buetti-Dinh, Antoine ; Licandro, Ginevra ; Ahmad, Paras ; Basoli, Valentina ; Alini, Mauro ; Stoddart, Martin J.

In: International journal of molecular sciences, 2021, vol. 22, no. 9, p. 16

Despite the huge body of research on osteogenic differentiation and bone tissue engineering, the translation potential of in vitro results still does not match the effort employed. One reason might be that the protocols used for in vitro research have inherent pitfalls. The synthetic glucocorticoid dexamethasone is commonly used in protocols for trilineage differentiation of human bone marrow...

Does mechanical stimulation really protect the architecture of trabecular bone? A simulation study

Maurer, Manfred ; Weinkamer, Richard ; Müller, Ralph ; Ruffoni, Davide

In: Biomechanics and Modeling in Mechanobiology, 2015, vol. 14, no. 4, p. 795-805

N -methyl pyrrolidone (NMP) inhibits lipopolysaccharide-induced inflammation by suppressing NF-κB signaling

Ghayor, Chafik ; Gjoksi, Bebeka ; Siegenthaler, Barbara ; Weber, Franz

In: Inflammation Research, 2015, vol. 64, no. 7, p. 527-536

Fortification of yogurts with vitamin D and calcium enhances the inhibition of serum parathyroid hormone and bone resorption markers: A double blind randomized controlled trial in women over 60 living in a community dwelling home

Bonjour, Jean-Philippe ; Benoit, V. ; Atkin, S. ; Walrand, S.

In: The journal of nutrition, health & aging, 2015, vol. 19, no. 5, p. 563-569

Regional Radiation Pneumonitis After SIRT of a Subcapsular Liver Metastasis: What is the Effect of Direct Beta Irradiation?

Dobrocky, Tomas ; Fuerstner, Markus ; Klaeser, Bernd ; Lopez-Benitez, Ruben ; Wälti, Yara ; Kara, Levent

In: CardioVascular and Interventional Radiology, 2015, vol. 38, no. 4, p. 1025-1030

A three-dimensional in vitro dynamic micro-tissue model of cardiac scar formation

Occhetta, Paola ; Isu, Giuseppe ; Lemme, Marta ; Conficconi, Chiara ; Oertle, Philipp ; Räz, Christian ; Visone, Roberta ; Cerino, Giulia ; Plodinec, Marija ; Rasponi, Marco ; Marsano, Anna

In: Integrative Biology, 2018, vol. 10, no. 3, p. 174-183

Fluid-structure interaction simulations of cerebral arteries modeled by isotropic and anisotropic constitutive laws

Tricerri, Paolo ; Dedè, Luca ; Deparis, Simone ; Quarteroni, Alfio ; Robertson, Anne ; Sequeira, Adélia

In: Computational Mechanics, 2015, vol. 55, no. 3, p. 479-498

Effect of bone graft density on in vitro cell behavior with enamel matrix derivative

Miron, Richard ; Caluseru, Oana ; Guillemette, Vincent ; Zhang, Yufeng ; Buser, Daniel ; Chandad, Fatiha ; Sculean, Anton

In: Clinical Oral Investigations, 2015, vol. 19, no. 7, p. 1643-1651

Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow–derived stromal stem cells

Barrio-Hernandez, Inigo ; Jafari, Abbas ; Rigbolt, Kristoffer T.G. ; Hallenborg, Philip ; Sanchez-Quiles, Virginia ; Skovrind, Ida ; Akimov, Vyacheslav ; Kratchmarova, Irina ; Dengjel, Jörn ; Kassem, Moustapha ; Blagoev, Blagoy

In: Genome Research, 2020, vol. 30, no. 1, p. 127-137

Bone marrow–derived mesenchymal stem cells (MSCs) differentiate into osteoblasts upon stimulation by signals present in their niche. Because the global signaling cascades involved in the early phases of MSCs osteoblast (OB) differentiation are not well-defined, we used quantitative mass spectrometry to delineate changes in human MSCs proteome and phosphoproteome during the first 24 h of...

Recombinant expression of hydroxylated human collagen in Escherichia coli

Rutschmann, Christoph ; Baumann, Stephan ; Cabalzar, Jürg ; Luther, Kelvin ; Hennet, Thierry

In: Applied Microbiology and Biotechnology, 2014, vol. 98, no. 10, p. 4445-4455