In: Inflammation Research, 2015, vol. 64, no. 7, p. 527-536
|
In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 23, p. 4561-4575
|
In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 15, p. 2779-2792
|
In: Pharmacology, 2020, vol. 105, no. 9–10, p. 491–504
Background: Adipose tissue inflammation occurs not only in obesity but also in aging and is mechanistically linked with age-associated diseases. Studies show that ablation of the l-arginine-metabolizing enzyme arginase-II (Arg-II) reduces adipose tissue inflammation and improves glucose tolerance in obesity. However, the role of Arg-II in aging adipose tissue inflammation is not clear....
|
In: Frontiers in Physiology, 2019, vol. 10, p. -
Hypoxia plays a crucial role in the pathogenesis of cardiovascular diseases. Mitochondrial enzyme arginase type II (Arg-II) is reported to lead to endothelial dysfunction and enhance the expression of endothelial inflammatory adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). In this study, we investigate the role of Arg-II in...
|
In: Cells, 2019, vol. 8, no. 5, p. 388
Fluid shear stress stimulates endothelial nitric oxide synthase (eNOS) activation and nitric oxide (NO) production through multiple kinases, including protein kinase A (PKA), AMP-activated protein kinase (AMPK), AKT and Ca2+/calmodulin-dependent protein kinase II (CaMKII). Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an adaptor protein that...
|
In: Basic Research in Cardiology, 2014, vol. 109, no. 1, p. 1-15
|
In: Cell and Tissue Research, 2014, vol. 355, no. 3, p. 687-699
|
In: Angiogenesis, 2014, vol. 17, no. 2, p. 383-393
|
In: Applied Physics B, 2014, vol. 116, no. 2, p. 339-346
|