Università della Svizzera italiana

Development of broad‐spectrum human monoclonal antibodies for rabies post‐exposure prophylaxis

De Benedictis, Paola ; Minola, Andrea ; Rota Nodari, Elena ; Aiello, Roberta ; Zecchin, Barbara ; Salomoni, Angela ; Foglierini, Mathilde ; Agatic, Gloria ; Vanzetta, Fabrizia ; Lavenir, Rachel ; Lepelletier, Anthony ; Bentley, Emma ; Weiss, Robin ; Cattoli, Giovanni ; Capua, Ilaria ; Sallusto, Federica ; Wright, Edward ; Lanzavecchia, Antonio ; Bourhy, Hervé ; Corti, Davide

In: EMBO molecular medicine, 2016, vol. 8, no. 4, p. 407-421

Currently available rabies post‐exposure prophylaxis (PEP) for use in humans includes equine or human rabies immunoglobulins (RIG). The replacement of RIG with an equally or more potent and safer product is strongly encouraged due to the high costs and limited availability of existing RIG. In this study, we identified two broadly neutralizing human monoclonal antibodies that represent a...

Université de Fribourg

Prevalence of fosfomycin resistance among ESBL-producing Escherichia coli isolates in the community, Switzerland

Mueller, Linda ; Cimen, Cansu ; Poirel, Laurent  ; Descombes, Marie-Christine  ; Nordmann, Patrice 

In: European Journal of Clinical Microbiology & Infectious Diseases, 2019, vol. 38, no. 5, p. 945–949

Our aim was to evaluate the prevalence of fosfomycin-resistant strains among ESBL- producing Escherichia coli isolates recovered from community patients in Switzerland. A total of 1225 ESBL-producing E. coli isolates were collected between 2012 and 2013 from a private and community laboratory. Fosfomycin resistance was assessed by using the novel rapid fosfomycin/E. coli NP test and agar...

Consortium of Swiss Academic Libraries

Variability of SCC mec in the Zurich area

Ender, M. ; Burger, S. ; Sokoli, A. ; Zbinden, R. ; Berger-Bächi, B. ; Heusser, R. ; Senn, M. ; McCallum, N.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2009, vol. 28, no. 6, p. 647-653