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Variability of SCC mec in the Zurich area

Ender, M. ; Burger, S. ; Sokoli, A. ; Zbinden, R. ; Berger-Bächi, B. ; Heusser, R. ; Senn, M. ; McCallum, N.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2009, vol. 28, no. 6, p. 647-653

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    Titre
    • Variability of SCC mec in the Zurich area
    Auteur
    • Ender, M.. Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland
    • Burger, S.. Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland
    • Sokoli, A.. Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland
    • Zbinden, R.. Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland
    • Berger-Bächi, B.. Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland
    • Heusser, R.. Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland
    • Senn, M.. Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland
    • McCallum, N.. Institute of Medical Microbiology, University of Zurich, Gloriastrasse 32, 8006, Zurich, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • European Journal of Clinical Microbiology & Infectious Diseases, 2009, vol. 28, no. 6, p. 647-653. Springer-Verlag
    Autre version électronique
    Classification
    • Santé
    Identifiant OAI-PMH
    • oai:doc.rero.ch:322288
    Summary
    A periodic survey of methicillin-resistant Staphylococcus aureus (MRSA) in Zurich in 2004 and 2006 revealed a consistently low prevalence of MRSA. SCCmec and ccr typing showed fluctuations in the proportions of SCCmec types and in the carriage of mobile virulence determinants. Together with the presence of variant SCCmecs these findings suggest a high clonal diversity and level of SCCmec recombination. The prevalence of a local "drug clone", associated with low-level methicillin resistance and rapid growth, significantly decreased. This clone had spread among intraveneous drug users, steadily increasing from 1994 to 2001 and was dominant in 2001. Apparently, changes in the management of the Zurich drug scene have restricted the spread of this clone