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Consortium of Swiss Academic Libraries

Host genetics of invasive Aspergillus and Candida infections

Wójtowicz, Agnieszka ; Bochud, Pierre-Yves

In: Seminars in Immunopathology, 2015, vol. 37, no. 2, p. 173-186

Université de Fribourg

A novel study on the inhibitory effect of marine macroalgal extracts on hyphal growth and biofilm formation of candidemia isolates

El-Zawawy, Nessma A. ; El-Shenody, Rania A. ; Ali, Sameh S. ; El-Shetehy, Mohamed

In: Scientific Reports, 2020, vol. 10, no. 1, p. 9339

Biofilm formation and hyphal growth are considered to be the most serious virulence factors of Candida species in blood causing candidemia infections, which are difficult to treat due to the spread of resistant Candida isolates to most antifungal drugs. Therefore, in this study, we investigated the effect of different types and concentrations of selected macroalgal extracts from Cladostephus...

Université de Fribourg

Effect of 3-mercaptopyruvate sulfurtransferase deficiency on the development of multiorgan failure, inflammation, and wound healing in mice subjected to burn injury

Ahmad, Akbar ; Druzhyna, Nadiya ; Szabo, Csaba

In: Journal of Burn Care & Research, 2019, vol. 40, no. 2, p. 148–156

The gaseous transmitter hydrogen sulfide (H2S) has been implicated in various forms of critical illness. Here, we have compared the outcome of scald burn injury in wild- type mice and in mice deficient in 3-mercaptopyruvate sulfurtransferase (3-MST), a mammalian H2S-generating enzyme. Outcome variables included indices of organ injury, clinical chemistry parameters, and plasma levels of...