In: Systematic Biology, 2018, vol. 67, no. 1, p. 170-174
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In: Environmental and Resource Economics, 2015, vol. 60, no. 2, p. 191-213
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In: The Journal of Infectious Diseases, 2018, vol. 217, no. 2, p. 270-279
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In: Bioinformatics, 2018, vol. 34, no. 13, p. i519-i527
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In: Integrative Biology, 2016, vol. 8, no. 4, p. 409-430
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In: Virus Evolution, 2018, vol. 4, no. 1, p. -
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In: iScience, 2020, vol. 23, no. 3, p. 100932
Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here we show that granzyme B degrades multiple secreted virulence mediators from Listeria monocytogenes,...
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In: ACS Nano, 2020, vol. 14, no. 2, p. 1879–1887
Enteric viruses, such as enterovirus, norovirus, and rotavirus, are among the leading causes of disease outbreaks due to contaminated drinking and recreational water. Viruses are difficult to remove from water through filtration based on physical size exclusion—for example by gravity-driven filters—due to their nanoscale size. To understand virus removal in drinking water treatment ...
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In: Viruses, 2020, vol. 12, no. 1, p. 17 p
Human cytomegalovirus (HCMV) infects more than 70% of the human population worldwide. HCMV is responsible for high morbidity and mortality in immunocompromised patients and remains the leading viral cause of congenital birth defects. Despite considerable efforts in vaccine and therapeutic development, HCMV infection still represents an unmet clinical need and a life-threatening disease in...
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In: Journal of molecular and genetic medicine, 2013, vol. 7, p. 309-314
The monomer of influenza haemagglutinin is synthesized as a single polypeptide precursor that during maturation is cleaved by proteases into two active subunits. Other studies have demonstrated that the human Transmembrane Protease Serine 2 (TMPRSS2) can cleave the HA of human seasonal influenza viruses. Consequently, we have investigated the use of human Transmembrane Protease Serine 2 to...
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