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Targeting glycolysis in macrophages confers protection against pancreatic ductal adenocarcinoma

Penny, Hweixian Leong ; Sieow, Je Lin ; Gun, Sin Yee ; Lau, Mai Chan ; Lee, Bernett ; Tan, Jasmine ; Phua, Cindy ; Toh, Florida ; Nga, Yvonne ; Yeap, Wei Hseun ; Janela, Baptiste ; Kumar, Dilip ; Chen, Hao ; Yeong, Joe ; Kenkel, Justin A. ; Pang, Angela ; Lim, Diana ; Toh, Han Chong ; Hon, Tony Lim Kiat ; Johnson, Christopher I. ; Khameneh, Hanif Javanmard ; Mortellaro, Alessandra ; Engleman, Edgar G. ; Rotzschke, Olaf ; Ginhoux, Florent ; Abastado, Jean-Pierre ; Chen, Jinmiao ; Wong, Siew Cheng

In: International journal of molecular sciences, 2021, vol. 22, no. 12, p. 24

Inflammation in the tumor microenvironment has been shown to promote disease progression in pancreatic ductal adenocarcinoma (PDAC); however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model of PDAC, we demonstrate that macrophages from tumor-bearing mice exhibit elevated glycolysis. Macrophage- specific deletion of Glucose Transporter 1...

La communication transparente et participative des organisations : Une lecture croisée des approches communicationnelles de l’école de Palo Alto et d’Habermas appliquée aux usages des médias sociaux numériques

Asdourian, Bruno

In: Communication & organisation, 2015, no. 48, p. 125-137

L’objectif de cet article est de proposer un cadre théorique de la communication transparente et participative des organisations présentes sur les médias sociaux numériques. Un regard croisé entre la communication « contenu-relation » (école de Palo Alto) et les critères de l’agir communicationnel (Habermas) permet de prendre en compte les caractéristiques spécifiques de ces...

Magnetization transfer ratio in lesions rather than normal-appearing brain relates to disability in patients with multiple sclerosis

Amann, Michael ; Papadopoulou, Athina ; Andelova, Michaela ; Magon, Stefano ; Mueller-Lenke, Nicole ; Naegelin, Yvonne ; Stippich, Christoph ; Radue, Ernst ; Bieri, Oliver ; Kappos, Ludwig ; Sprenger, Till

In: Journal of Neurology, 2015, vol. 262, no. 8, p. 1909-1917

Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis

Barro, Christian ; Benkert, Pascal ; Disanto, Giulio ; Tsagkas, Charidimos ; Amann, Michael ; Naegelin, Yvonne ; Leppert, David ; Gobbi, Claudio ; Granziera, Cristina ; Yaldizli, Özgür ; Michalak, Zuzanna ; Wuerfel, Jens ; Kappos, Ludwig ; Parmar, Katrin ; Kuhle, Jens

In: Brain, 2018, vol. 141, no. 8, p. 2382-2391

Nine hole peg test and transcranial magnetic stimulation: useful to evaluate dexterity of the hand and disease progression in amyotrophic lateral sclerosis

Czell, David ; Neuwirth, Christoph ; Weber, Markus ; Sartoretti-Schefer, Sabine ; Gutzeit, Andreas ; Reischauer, Carolin

In: Neurology Research International, 2019, vol. 2019, p. 1–5

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with involvement of the upper and lower motor neurons. Since the loss of fine motor skills is one of the earliest signs of ALS, the hypothesis was tested if the nine hole PEG test (NHPT) and transcranial magnet stimulation (TMS) with resting-motor threshold (RMT) could be useful in monitoring disease progression. Methods. We...

A novel approach to study radiation track structure with nanometer-equivalent resolution

Casiraghi, Margherita ; Bashkirov, Vladimir ; Hurley, Ford ; Schulte, Reinhard

In: The European Physical Journal D, 2014, vol. 68, no. 5, p. 1-6

Non-Existence of Multiple-Black-Hole Solutions Close to Kerr-Newman

Wong, Willie ; Yu, Pin

In: Communications in Mathematical Physics, 2014, vol. 325, no. 3, p. 965-996

Head Motion Parameters in fMRI Differ Between Patients with Mild Cognitive Impairment and Alzheimer Disease Versus Elderly Control Subjects

Haller, Sven ; Monsch, Andreas ; Richiardi, Jonas ; Barkhof, Frederik ; Kressig, Reto ; Radue, Ernst

In: Brain Topography, 2014, vol. 27, no. 6, p. 801-807

N-terminal pro-B-type natriuretic peptide and functional capacity in patients with obstructive sleep apnea

Maeder, Micha ; Ammann, Peter ; Rickli, Hans ; Schoch, Otto ; Korte, Wolfgang ; Hürny, Christoph ; Myers, Jonathan ; Münzer, Thomas

In: Sleep and Breathing, 2008, vol. 12, no. 1, p. 7-16

Leveraging 3D City Models for Rotation Invariant Place-of-Interest Recognition

Baatz, Georges ; Köser, Kevin ; Chen, David ; Grzeszczuk, Radek ; Pollefeys, Marc

In: International Journal of Computer Vision, 2012, vol. 96, no. 3, p. 315-334