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Università della Svizzera italiana

Electrolyte and acid-base disorders triggered by aminoglycoside or colistin therapy : a systematic review

Scoglio, Martin ; Bronz, Gabriel ; Rinoldi, Pietro O. ; Faré, Pietro B. ; Betti, Céline ; Bianchetti, Mario G. ; Simonetti, Giacomo D. ; Gennaro, Viola ; Renzi, Samuele ; Lava, Sebastiano A. G. ; Milani, Gregorio P.

In: Antibiotics, 2021, vol. 10, no. 2, p. 9

Aminoglycoside or colistin therapy may alter the renal tubular function without decreasing the glomerular filtration rate. This association has never been extensively investigated. We conducted a systematic review of the literature following the Preferred Reporting Items for Systematic Reviews and Meta- Analyses recommendations. Databases searched included United States National Library of...

Università della Svizzera italiana

Maintenance fluid therapy with saline, dextrose-supplemented saline or lactated Ringer in childhood: short-term metabolic effects

Ricciuti, Alessandra ; Milani, Gregorio P. ; Tarantino, Silvia ; Ghilardi, Roberta ; Lava, Sebastiano A.G. ; Alberzoni, Marco ; Bianchetti, Mario G. ; Agostoni, Carlo

In: Nutrients, 2020, vol. 12, no. 5, p. 8 p

Maintenance with isotonic fluids is recommended in children with gastroenteritis and failure of oral rehydration therapy. However, little is known on the short-term effects of the commonly prescribed intravenous solutions on metabolic balance in children. The aim of this study is to report on our experience with normal saline, dextrose-supplemented saline and lactated Ringer solution. Methods:...