In: Age and Ageing, 2018, vol. 47, no. 5, p. 760-760
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In: Clinical Rheumatology, 2015, vol. 34, no. 3, p. 591-596
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In: Current Infectious Disease Reports, 2015, vol. 17, no. 4, p. 1-11
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In: Virus Evolution, 2018, vol. 4, no. 2, p. -
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In: Current Infectious Disease Reports, 2015, vol. 17, no. 6, p. 1-5
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In: Nature communications, 2015, vol. 6, p. 6163
Glycoprotein G (gG) from herpes simplex virus 1 and 2 (HSV-1 and HSV-2, important human neurotropic pathogens) is the first viral chemokine-binding protein found to potentiate chemokine function. Here we show that gG attaches to cell surface glycosaminoglycans and induces lipid raft clustering, increasing the incorporation of CXCR4 receptors into these microdomains. gG induces conformational...
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In: Plos pathogens, 2012, vol. 8, no. 2, p. e1002497
Herpes simplex virus (HSV) types 1 and 2 are highly prevalent human neurotropic pathogens that cause a variety of diseases, including lethal encephalitis. The relationship between HSV and the host immune system is one of the main determinants of the infection outcome. Chemokines play relevant roles in antiviral response and immunopathology, but the modulation of chemokine function by HSV is...
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In: Infection, 2014, vol. 42, no. 4, p. 779-783
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In: Scientific Reports, 2019, vol. 9, no. 1, p. 4833
The neurotropic Japanese encephalitis virus (JEV) is responsible for Japanese encephalitis, an uncontrolled inflammatory disease of the central nervous system. Microglia cells are the unique innate immune cell type populating the brain that cross- communicate with neurons via the CX3CR1-CX3CL1 axis. However, microglia may serve as a viral reservoir for JEV. Human microglia are able to transmit...
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In: European Archives of Oto-Rhino-Laryngology, 2010, vol. 267, no. 7, p. 1089-1093
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