In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 2, p. 376-384
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In: Journal of Antimicrobial Chemotherapy, 2016, vol. 71, no. 12, p. 3624-3624
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In: Genetics, 2020, vol. 216, no. 4, p. 931–945
Differential gene expression across cell types underlies development and cell physiology in multicellular organisms. Caenorhabditis elegans is a powerful, extensively used model to address these biological questions. A remaining bottleneck relates to the difficulty to obtain comprehensive tissue-specific gene transcription data, since available methods are still challenging to execute and/or...
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In: Journal of Infection, 2020, vol. 80, no. 1, p. 121–142
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In: Plos pathogens, 2013, vol. 9, no. 1, p. e1003130
An understanding of the immunological footprint of Mycobacterium tuberculosis (MTB) CD4 T cell recognition is still incomplete. Here we report that human Th1 cells specific for MTB are largely contained in a CXCR3+CCR6+ memory subset and highly focused on three broadly immunodominant antigenic islands, all related to bacterial secretion systems. Our results refute the notion that secreted...
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In: European Journal of Pediatrics, 2014, vol. 173, no. 4, p. 457-462
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In: Der Gastroenterologe, ///-
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In: European Journal of Pediatrics, 2014, vol. 173, no. 3, p. 331-336
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In: Natural Product Research, 2019, vol. 33, no. 5, p. 642–650
Triclisinone (2), a new ochnaflavone derivative, was isolated from the aerial parts of Triclisia gilletii, along with known drypemolundein B (1) and eight other known compounds. The chemical shifts of drypemolundein B (1) have been partially revised based on reinterpretation of NMR spectroscopic data. The eight other secondary metabolites are composed of: (+)-nonacosan-10-ol (3); stigmasterol...
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In: Proceedings of the national academy of sciences of the United States of America, 2015, vol. 112, no. 2, p. E147-E155
A previous unbiased genome-wide analysis of CD4 Mycobacterium tuberculosis (MTB) recognition using peripheral blood mononuclear cells from individuals with latent MTB infection (LTBI) or nonexposed healthy controls (HCs) revealed that certain MTB sequences were unexpectedly recognized by HCs. In the present study, it was found that, based on their pattern of reactivity, epitopes could be...
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