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Richter syndrome

Condoluci, Adalgisa ; Rossi, Davide

In: Current Oncology Reports, 2021, vol. 23, no. 3, p. 10

Purpose of Review Richter syndrome (RS) is an uncommon but aggressive evolution of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). RS is an unmet clinical need in the field of CLL. Recent advances in understanding the biology of this condition provide the rationale for testing new therapeutic concepts in order to improve the outcome of patients developing RS, which is so far...

Population mixing and the risk of childhood leukaemia in Switzerland: a census-based cohort study

Lupatsch, Judith ; Kuehni, Claudia ; Niggli, Felix ; Ammann, Roland ; Egger, Matthias ; Spycher, Ben

In: European Journal of Epidemiology, 2015, vol. 30, no. 12, p. 1287-1298

The role of hematopoietic stem cell transplantation in chronic myeloid leukemia

Gratwohl, Alois ; Baldomero, Helen ; Passweg, Jakob

In: Annals of Hematology, 2015, vol. 94, p. 177-186

Health-related quality of life in young survivors of childhood cancer

Wengenroth, L. ; Gianinazzi, M. ; Rueegg, C. ; Lüer, S. ; Bergstraesser, E. ; Kuehni, C. ; Michel, G.

In: Quality of Life Research, 2015, vol. 24, no. 9, p. 2151-2161

Overweight in childhood cancer survivors: the Swiss Childhood Cancer Survivor Study

Belle, Fabiën N. ; Weiss, Annette ; Schindler, Matthias ; Goutaki, Myrofora ; Bochud, Murielle ; Zimmermann, Karin ; von der Weid, Nicolas ; Ammann, Roland A. ; Kuehni, Claudia E.

In: The American Journal of Clinical Nutrition, 2018, vol. 107, no. 1, p. 3-11

Childhood cancer and residential exposure to highways: a nationwide cohort study

Spycher, Ben ; Feller, Martin ; Röösli, Martin ; Ammann, Roland ; Diezi, Manuel ; Egger, Matthias ; Kuehni, Claudia

In: European Journal of Epidemiology, 2015, vol. 30, no. 12, p. 1263-1275

Expression of KIR2DS1 does not significantly contribute to NK cell cytotoxicity in HLA-C1/C2 heterozygous haplotype B donors

Baltner, Karla ; Kübler, Ayline ; Pal, Marina ; Balvočiūte, Monika ; Mezger, Markus ; Handgretinger, Rupert ; André, Maya C.

In: International Immunology, 2017, vol. 29, no. 9, p. 423-429

Serum cholesterol acceptor capacity in intrauterine growth restricted fetuses

Pecks, Ulrich ; Rath, Werner ; Bauerschlag, Dirk O. ; Maass, Nicolai ; Orlikowsky, Thorsten ; Mohaupt, Markus G. ; Escher, Geneviève

In: Journal of Perinatal Medicine, 2017, vol. 45, no. 7, p. 829-835

Lymphocyte doubling time in chronic lymphocytic leukemia modern era : a real-life study in 848 unselected patients

Baumann, Tycho ; Moia, Riccardo ; Gaidano, Gianluca ; Delgado, Julio ; Condoluci, Adalgisa ; Villamor, Neus ; Payedimarri, Anil Babu ; Costa, Dolors ; Patriarca, Andrea ; Jiménez-Vicente, Carlos ; Rossi, Davide ; Montserrat, Emili

In: Leukemia, 2021, p. 7 p

The prognostic significance of lymphocyte doubling time (LDT) in chronic lymphocytic leukemia (CLL) was identified when the biology of the disease was poorly understood and therapy was not effective. We assessed the clinical and biological significance of LDT in 848 CLL patients in a real-life setting and the context of new biomarkers and effective therapy. A short LDT (≤12 months) was...

Higher-order connections between stereotyped subsets : implications for improved patient classification in CLL

Agathangelidis, Andreas ; Chatzidimitriou, Anastasia ; Gemenetzi, Katerina ; Giudicelli, Veronique ; Karypidou, Maria ; Plevova, Karla ; Davis, Zadie ; Yan, Xiao-Jie ; Jeromin, Sabine ; Schneider, Christof ; Bredo-Pedersen, Lone ; Tschumper, Renee C. ; Sutton, Lesley-Ann ; Baliakas, Panagiotis ; Scarfò, Lydia ; van Gastel, Ellen J. ; Armand, Marine ; Tausch, Eugen ; Biderman, Bella ; Baer, Constance ; Bagnara, Davide ; Navarro, Alba ; Langlois de Septenville, Anne ; Guido, Valentina ; Mitterbauer-Hohendanner, Gerlinde ; Dimovski, Aleksandar ; Brieghel, Christian ; Lawless, Sarah ; Meggendorfer, Manja ; Braazdilova, Kamila ; Ritgen, Matthias ; Facco, Monica ; Tresoldi, Cristina ; Visentin, Andrea ; Patriarca, Andrea ; Catherwood, Mark ; Bonello, Lisa ; Sudarikov, Andrey ; Vanura, Katrina ; Roumelioti, Maria ; Skuhrova-Francova, Hana ; Moysiadis, Theodoros ; Veronese, Silvio ; Giannopoulos, Krzysztof ; Mansouri, Larry ; Karan-Djurasevic, Teodora ; Sandaltzopoulos, Raphael ; Bödör, Csaba ; Fais, Franco ; Kater, Arnon ; Panovska, Irina ; Rossi, Davide ; Alshemmari, Salem ; Panagiotidis, Panagiotis ; Costeas, Paul ; Espinet Solà, Blanca ; Antic, Darko ; Foroni, Letizia ; Montillo, Marco ; Trentin, Livio ; Stavroyianni, Niki ; Gaidano, Gianluca ; Francia di Celle, Paola ; Niemann, Carsten ; Campo, Elias ; Anagnostopoulos, Achilles ; Pott, Christiane ; Fischer, Kirsten ; Hallek, Michael ; Oscier, David ; Stilgenbauer, Stephan ; Haferlach, Claudia ; Jelinek, Diane ; Chiorazzi, Nicholas ; Pospisilova, Sarka ; Lefranc, Marie-Paule ; Kossida, Sofia ; Langerak, Anton W. ; Belessi, Chrysoula ; Davi, Frederic ; Rosenquist, Richard ; Ghia, Paolo ; Stamatopoulos, Kostas

In: Blood, 2020, vol. 137, no. 10, p. 1365–1376

Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets of patients with (quasi)identical, stereotyped B cell receptor immunoglobulins (BcR IG). Patients in certain major stereotyped subsets often display remarkably consistent clinicobiological profiles, suggesting that the study of BcR IG stereotypy in CLL has important implications for understanding disease...