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Consortium of Swiss Academic Libraries

Live Virus Vaccines in Transplantation: Friend or Foe?

Verolet, Charlotte ; Posfay-Barbe, Klara

In: Current Infectious Disease Reports, 2015, vol. 17, no. 4, p. 1-11

Consortium of Swiss Academic Libraries

Inferring the age difference in HIV transmission pairs by applying phylogenetic methods on the HIV transmission network of the Swiss HIV Cohort Study

Kusejko, Katharina ; Kadelka, Claus ; Marzel, Alex ; Battegay, Manuel ; Bernasconi, Enos ; Calmy, Alexandra ; Cavassini, Matthias ; Hoffmann, Matthias ; Böni, Jürg ; Yerly, Sabine ; Klimkait, Thomas ; Perreau, Matthieu ; Rauch, Andri ; Günthard, Huldrych F. ; Kouyos, Roger D. ; Scherrer, Alexandra ; Wild, Susanne ; Perraudin, Danièle ; Minichiello, Mirjam ; Anagnostopoulos, A. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Braun, D L. ; Bucher, H C. ; Calmy, A. ; Cavassini, M. ; Ciuffi, A. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, C A. ; Günthard, H F. ; Haerry, D. ; Hasse, B. ; Hirsch, H H. ; Hoffmann, M. ; Hösli, I. ; Huber, M. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R D. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Marzolini, C. ; Metzner, K J. ; Müller, N. ; Nicca, D. ; Paioni, P. ; Pantaleo, G. ; Perreau, M. ; Rauch, A. ; Rudin, C. ; Scherrer, A U. ; Schmid, P. ; Speck, R. ; Stöckle, M. ; Tarr, P. ; Trkola, A. ; Vernazza, P. ; Wandeler, G. ; Weber, R. ; Yerly, S Morover ; Scherrer, Alexandra ; Wild, Susanne ; Perraudin, Danièle ; Minichiello, Mirjam ; Anagnostopoulos, A. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Braun, D L. ; Bucher, H C. ; Calmy, A. ; Cavassini, M. ; Ciuffi, A. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, C A. ; Günthard, H F. ; Haerry, D. ; Hasse, B. ; Hirsch, H H. ; Hoffmann, M. ; Hösli, I. ; Huber, M. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R D. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Marzolini, C. ; Metzner, K J. ; Müller, N. ; Nicca, D. ; Paioni, P. ; Pantaleo, G. ; Perreau, M. ; Rauch, A. ; Rudin, C. ; Scherrer, A U. ; Schmid, P. ; Speck, R. ; Stöckle, M. ; Tarr, P. ; Trkola, A. ; Vernazza, P. ; Wandeler, G. ; Weber, R. ; Yerly, S Morover

In: Virus Evolution, 2018, vol. 4, no. 2, p. -

Consortium of Swiss Academic Libraries

Reply to Planet et al

François, Patrice ; von Dach, Elodie ; Diene, Seydina M. ; Harbarth, Stephan ; Schrenzel, Jacques

In: The Journal of Infectious Diseases, 2016, vol. 214, no. 10, p. 1610-1611

Università della Svizzera italiana

Structure and function analysis of an antibody recognizing all influenza A subtypes

Kallewaard, Nicole L. ; Corti, Davide ; Collins, Patrick J. ; Neu, Ursula ; McAuliffe, Josephine M. ; Benjamin, Ebony ; Wachter-Rosati, Leslie ; Palmer-Hill, Frances J. ; Yuan, Andy Q. ; Walker, Philip A. ; Vorlaender, Matthias K. ; Bianchi, Siro ; Guarino, Barbara ; De Marco, Anna ; Vanzetta, Fabrizia ; Agatic, Gloria ; Foglierini, Mathilde ; Pinna, Debora ; Fernandez-Rodriguez, Blanca ; Fruehwirth, Alexander ; Silacci, Chiara ; Ogrodowicz, Roksana W. ; Martin, Stephen R. ; Sallusto, Federica ; Suzich, JoAnn A. ; Lanzavecchia, Antonio ; Zhu, Qing ; Gamblin, Steven J. ; Skehel, John J.

In: Cell, 2016, vol. 166, no. 3, p. 596-608

Influenza virus remains a threat because of its ability to evade vaccine-induced immune responses due to antigenic drift. Here, we describe the isolation, evolution, and structure of a broad-spectrum human monoclonal antibody (mAb), MEDI8852, effectively reacting with all influenza A hemagglutinin (HA) subtypes. MEDI8852 uses the heavy-chain VH6-1 gene and has higher potency and breadth when...

Università della Svizzera italiana

Identification and structure of a multidonor class of head-directed influenza-neutralizing antibodies reveal the mechanism for its recurrent elicitation

Sao-Fong Cheung, Crystal ; Fruehwirth, Alexander ; Paparoditis, Philipp Carl Georg ; Shen, Chen-Hsiang ; Foglierini, Mathilde ; Joyce, M. Gordon ; Leung, Kwanyee ; Piccoli, Luca ; Rawi, Reda ; Silacci-Fregni, Chiara ; Tsybovsky, Yaroslav ; Verardi, Raffaello ; Wang, Lingshu ; Wang, Shuishu ; Yang, Eun Sung ; Zhang, Baoshan ; Zhang, Yi ; Chuang, Gwo-Yu ; Corti, Davide ; Mascola, John R. ; Shapiro, Lawrence ; Kwong, Peter D. ; Lanzavecchia, Antonio ; Zhou, Tongqing

In: Cell reports, 2020, vol. 32, no. 9, p. 12 p

Multidonor antibodies are of interest for vaccine design because they can in principle be elicited in the general population by a common set of immunogens. For influenza, multidonor antibodies have been observed against the hemagglutinin (HA) stem, but not the immunodominant HA head. Here, we identify and characterize a multidonor antibody class (LPAF-a class) targeting the HA head. This class...

Università della Svizzera italiana

Diabetes mellitus is a risk factor for prolonged SARS-CoV-2 viral shedding in lower respiratory tract samples of critically ill patients

Buetti, Niccolò ; Trimboli, Pierpaolo ; Mazzuchelli, Timothy ; Lo Priore, Elia ; Balmelli, Carlo ; Trkola, Alexandra ; Conti, Marco ; Martinetti, Gladys ; Elzi, Luigia ; Ceschi, Alessandro ; Consonni, Vera ; Ogna, Adam ; Forni-Ogna, Valentina ; Bernasconi, Enos

In: Endocrine, 2020, p. 7 p

The length of time a critically ill coronavirus disease 2019 (COVID-19) patient remains infectious and should therefore be isolated remains unknown. This prospective study was undertaken in critically ill patients to evaluate the reliability of single negative real-time polymerase chain reaction (RT-PCR) in lower tracheal aspirates (LTA) in predicting a second negative test and to analyze...

Université de Fribourg

Breast milk microbiota: A review of the factors that influence composition

Zimmermann, Petra ; Curtis, Nigel

In: Journal of Infection, 2020, vol. 81, no. 1, p. 17–47

Breastfeeding is associated with considerable health benefits for infants. Aside from essential nutrients, immune cells and bioactive components, breast milk also contains a diverse range of microbes, which are important for maintaining mammary and infant health. In this review, we summarise studies that have investigated the composition of the breast milk microbiota and factors that might...