Affiner les résultats

Collection spécifique

Langue

Università della Svizzera italiana

The Mre11-Nbs1 interface is essential for viability and tumor suppression

Kim, Jun Hyun ; Grosbart, Malgorzata ; Anand, Roopesh ; Wyman, Claire ; Cejka, Petr ; Petrini, John H.J.

In: Cell reports, 2017, vol. 18, no. 2, p. 496-507

The Mre11 complex (Mre11, Rad50, and Nbs1) is integral to both DNA repair and ataxia telangiectasia mutated (ATM)-dependent DNA damage signaling. All three Mre11 complex components are essential for viability at the cellular and organismal levels. To delineate essential and non-essential Mre11 complex functions that are mediated by Nbs1, we used TALEN-based genome editing to derive Nbs1...

Université de Fribourg

Resolute zotarolimus‐eluting stent in ST‐elevation myocardial infarction (resolute‐STEMI): A prespecified prospective register from the DAPT‐STEMI trial

Postma, Warner ; Fabris, Enrico ; Ent, Martin Van der ; Hermanides, Rik ; Buszman, Pawel ; Birgelen, Clemens Von ; Cook, Stéphane ; Wedel, Hans ; Luca, Giuseppe De ; Delewi, Ronak ; Zijlstra, Felix ; Kedhi, Elvin

In: Catheterization and Cardiovascular Interventions, 2019, p. ccd.28376

To evaluate the safety and efficacy outcomes after primary percutaneous coronary intervention (pPCI) with second‐generation Resolute™ zotarolimus‐eluting stent (R‐ ZES) in patients enrolled in the DAPT‐STEMI Trial (NCT01459627).Background: R‐ ZES is one of the most used drug eluting stents worldwide. To date, the safety and efficacy data of this stent in setting of STEMI is...

Université de Fribourg

Absorb bioresorbable scaffold versus xience metallic stent for prevention of restenosis following percutaneous coronary intervention in patients at high risk of restenosis: rationale and design of the COMPARE ABSORB trial

Chang, Chun Chin ; Onuma, Yoshinobu ; Achenbach, Stephan ; Barbato, Emanuele ; Chevalier, Bernard ; Cook, Stéphane ; Dudek, Dariusz ; Escaned, Javier ; Gori, Tommaso ; Kočka, Viktor ; Tarantini, Giuseppe ; E.J.West, Nick ; Morice, Marie-Claude ; G.P.Tijssen, Jan ; Geuns, Robert-Janvan ; C.Smits, Pieter

In: Cardiovascular Revascularization Medicine, 2019, vol. 20, no. 7, p. 577–582

Background: The advent of bioresorbable vascular scaffolds (BVS) was considered as a potential improvement in percutaneous coronary intervention (PCI) after the groundbreaking development of drug eluting stents (DES). However, the clinical performance, long-term safety and efficacy of BVS in complex coronary lesions remain uncertain. COMPARE ABSORB, a multicenter, single blind, prospective ...

Consortium of Swiss Academic Libraries

The impact of cardiac CT on the appropriate utilization of catheter coronary angiography

Wagdi, Philipp ; Alkadhi, Hatem

In: The International Journal of Cardiovascular Imaging, 2010, vol. 26, no. 3, p. 333-344