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Université de Fribourg

Cross-border emergence of Escherichia coli producing the carbapenemase NDM-5 in Switzerland and Germany

Chakraborty, Trinad ; Sadek, Mustafa ; Yao, Yancheng ; Imirzalioglu, Can ; Stephan, Roger ; Poirel, Laurent ; Nordmann, Patrice

In: Journal of Clinical Microbiology, 2020, p. -

A series of clinical NDM-5-producing E. coli isolates obtained from two surveillance networks of carbapenem-producing Enterobacterales from 2018-2019, namely Switzerland (NARA) and Germany (SurvCARE), were analyzed. The 33 NDM-5- producing E. coli isolates were highly resistant to β-lactams including the novel ß- lactam/ß-lactamase inhibitor combinations (ceftazidime/avibactam, ...

Université de Fribourg

Catheter-related infections: does the spectrum of microbial causes change over time? A nationwide surveillance study

Buetti, Niccolò ; Priore, Elia Lo ; Atkinson, Andrew ; Widmer, Andreas F ; Kronenberg, Andreas ; Marschall, Jonas ; Swiss Centre for Antibiotic Resistance (ANRESIS)

In: BMJ Open, 2018, vol. 8, no. 12, p. e023824

Objectives To estimate the incidence and epidemiology of catheter-related bloodstream infections (CRBSIs) on a national scale by using prospective epidemiological data from the Swiss Antibiotic Resistance Surveillance System (ANRESIS). Design Observational study. Setting National surveillance from 2008 to 2015 of acute hospitals in Switzerland. Participants We included acute Swiss hospitals...

Université de Fribourg

Rapid detection of fosfomycin resistance in Escherichia coli

Nordmann, Patrice ; Poirel, Laurent ; Mueller, Linda

In: Journal of Clinical Microbiology, 2019, vol. 57, no. 1, p. e01531-18

The rapid fosfomycin/Escherichia coli NP test was developed to detect fosfomycin resistance in E. coli isolates. The test is based on glucose metabolization and the detection of bacterial growth in the presence of fosfomycin at 40 µg/ml. Bacterial growth is visually detectable by an orange-to-yellow color change of red phenol, a pH indicator. A total of 100 E. coli isolates, among which 22...