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The extended, dynamic mitochondrial reticulum in skeletal muscle and the creatine kinase (CK)/phosphocreatine (PCr) shuttle are working hand in hand for optimal energy provision

Wallimann, Theo

In: Journal of Muscle Research and Cell Motility, 2015, vol. 36, no. 4-5, p. 297-300

Ataxia, Intellectual Disability, and Ocular Apraxia with Cerebellar Cysts: A New Disease?

Poretti, Andrea ; Häusler, Martin ; von Moers, Arpad ; Baumgartner, Bastian ; Zerres, Klaus ; Klein, Andrea ; Aiello, Chiara ; Moro, Francesca ; Zanni, Ginevra ; Santorelli, Filippo ; Huisman, Thierry ; Weis, Joachim ; Valente, Enza ; Bertini, Enrico ; Boltshauser, Eugen

In: The Cerebellum, 2014, vol. 13, no. 1, p. 79-88

Spatially distinct pools of TORC1 balance protein homeostasis

Hatakeyama, Riko ; Péli-Gulli, Marie-Pierre ; Hu, Zehan ; Jaquenoud, Malika ; Osuna, Guillermo Miguel Garcia ; Sardu, Alessandro ; Dengjel, Jörn ; Virgilio, Claudio De

In: Molecular Cell, 2019, vol. 73, no. 2, p. 325-338.e8

The eukaryotic TORC1 kinase is a homeostatic controller of growth that integrates nutritional cues and mediates signals primarily from the surface of lysosomes or vacuoles. Amino acids activate TORC1 via the Rag GTPases that combine into structurally conserved multi-protein complexes such as the EGO complex (EGOC) in yeast. Here we show that Ego1, which mediates membrane-anchoring of EGOC via...

The murine orthologue of the Golgi-localized TPTE protein provides clues to the evolutionary history of the human TPTE gene family

Guipponi, Michel ; Tapparel, Caroline ; Jousson, Olivier ; Scamuffa, Nathalie ; Mas, Christophe ; Rossier, Colette ; Hutter, Pierre ; Meda, Paolo ; Lyle, Robert ; Reymond, Alexandre ; Antonarakis, Stylianos

In: Human Genetics, 2001, vol. 109, no. 6, p. 569-575

Expressing creatine kinase in transgenic tobacco - a first step towards introducing an energy buffering system in plants

Farrés, Judith ; Holmberg, Niklas ; Schlattner, Uwe ; Bailey, James ; Wallimann, Theo ; Kallio, Pauli

In: Transgenic Research, 2002, vol. 11, no. 1, p. 49-59

Creatine deficiency syndromes and the importance of creatine synthesis in the brain

Braissant, Olivier ; Henry, Hugues ; Béard, Elidie ; Uldry, Joséphine

In: Amino Acids, 2011, vol. 40, no. 5, p. 1315-1324

In vivo measurement of glycine with short echo-time 1H MRS in human brain at 7 T

Gambarota, Giulio ; Mekle, Ralf ; Xin, Lijing ; Hergt, Martin ; van der Zwaag, Wietske ; Krueger, Gunnar ; Gruetter, Rolf

In: Magnetic Resonance Materials in Physics, Biology and Medicine, 2009, vol. 22, no. 1, p. 1-4

JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis

Abdelli, S. ; Puyal, J. ; Bielmann, C. ; Buchillier, V. ; Abderrahmani, A. ; Clarke, P. ; Beckmann, J. ; Bonny, C.

In: Diabetologia, 2009, vol. 52, no. 9, p. 1871-1880

The creatine kinase system and pleiotropic effects of creatine

Wallimann, Theo ; Tokarska-Schlattner, Malgorzata ; Schlattner, Uwe

In: Amino Acids, 2011, vol. 40, no. 5, p. 1271-1296

AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: A review

Braissant, O. ; Henry, H.

In: Journal of Inherited Metabolic Disease, 2008, vol. 31, no. 2, p. 230-239