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Consortium of Swiss Academic Libraries

Unipolar mania: a necessary diagnostic concept

Angst, Jules ; Grobler, Christoffel

In: European Archives of Psychiatry and Clinical Neuroscience, 2015, vol. 265, no. 4, p. 273-280

Université de Fribourg

Alpha‐synuclein dopaminylation presented in plasma of both healthy subjects and parkinson’s disease patients

Zhao, Huiyuan ; Huang, Shuai ; Palanisamy, Sivakumar ; Wang, Cui ; Rainer, Gregor ; Zhang, Xiaozhe

In: PROTEOMICS – Clinical Applications, 2020, vol. 14, no. 5, p. 1900117

Alpha‐synuclein (α‐syn) dopaminylation can lead to the death of dopaminergic neurons in the brain and is a risk factor of Parkinson's disease (PD). This study aims to examine whether such a posttranslational modification (PTM) is presented in human blood plasma. Experimental Design: In vitro reaction simulation between α‐syn and dopamine (DA) is conducted to study the biochemical...