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Pathological Gambling Induced by Dopamine Antagonists: A Case Report

Grötsch, Philipp ; Lange, Claudia ; Wiesbeck, Gerhard ; Lang, Undine

In: Journal of Gambling Studies, 2015, vol. 31, no. 1, p. 295-297

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    Titre
    • Pathological Gambling Induced by Dopamine Antagonists: A Case Report
    Auteur
    • Grötsch, Philipp. Psychiatric Hospital of the University of Basel, Wilhelm Klein-Strasse 27, 4012, Basel, Switzerland
    • Lange, Claudia. Psychiatric Hospital of the University of Basel, Wilhelm Klein-Strasse 27, 4012, Basel, Switzerland
    • Wiesbeck, Gerhard. Psychiatric Hospital of the University of Basel, Wilhelm Klein-Strasse 27, 4012, Basel, Switzerland
    • Lang, Undine. Psychiatric Hospital of the University of Basel, Wilhelm Klein-Strasse 27, 4012, Basel, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Journal of Gambling Studies, 2015, vol. 31, no. 1, p. 295-297. Springer US; http://www.springer-ny.com
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:332202
    Summary
    Pathological gambling is defined as inappropriate, persistent, and maladaptive gambling behaviour. It is a non-pharmacological addiction classified as an impulse control disorder. However, pathological gambling has been associated with dopamine agonist use. Here we report of a 28-year-old man with a first major depressive episode and a post-traumatic stress disorder who has been treated with a combination of the serotonine/noradrenaline reuptake inhibitor duloxetine and the tricyclic antidepressant maprotiline. The administration of antipsychotic flupentixole (up to 7mg) turned this slight online poker gambler into an excessive gambler. Only after the discontinuation of the antidopaminergic agents and the switch to bupropion did this gambling behaviour stop which suggests a causal relationship between dopamine antagonists and pathological gambling.