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Università della Svizzera italiana

GEASI : Geodesic-based earliest activation sites identification in cardiac models

Grandits, Thomas ; Effland, Alexander ; Pock, Thomas ; Krause, Rolf ; Plank, Gernot ; Pezzuto, Simone

In: International journal for numerical methods in biomedical engineering, 2021, vol. 37, no. 8, p. 30

The identification of the initial ventricular activation sequence is a critical step for the correct personalization of patient- specific cardiac models. In healthy conditions, the Purkinje network is the main source of the electrical activation, but under pathological conditions the so-called earliest activation sites (EASs) are possibly sparser and more localized. Yet, their number, location...

Consortium of Swiss Academic Libraries

Sarcoma of the heart: survival after surgery

Niclauss, Lars ; Montemurro, Michael ; Kirsch, Matthias ; Prêtre, René

In: Interactive CardioVascular and Thoracic Surgery, 2018, vol. 27, no. 2, p. 198-201

Università della Svizzera italiana

Space-time multilevel Monte Carlo methods and their application to cardiac electrophysiology

Ben Bader, Seif ; Benedusi, Pietro ; Quaglino, Alessio ; Zulian, Patrick ; Krause, Rolf

In: Journal of computational physics, 2021, vol. 433, p. 17 p

We present a novel approach aimed at high-performance uncertainty quantification for time-dependent problems governed by partial differential equations. In particular, we consider input uncertainties described by a Karhunen-Loève expansion and compute statistics of high-dimensional quantities-of-interest, such as the cardiac activation potential. Our methodology relies on a close integration...