Refine my results

Document type

Specific Collection

Language

Università della Svizzera italiana

Changes in breast cancer management during the Corona Virus Disease 19 pandemic : an international survey of the European Breast Cancer Research Association of Surgical Trialists (EUBREAST)

Gasparri, Maria Luisa ; Gentilini, Oreste Davide ; Lueftner, Diana ; Kuehn, Thorsten ; Kaidar-Person, Orit ; Poortmans, Philip

In: The breast, 2020, vol. 52, p. 110-115

Background: Corona Virus Disease 19 (COVID-19) had a worldwide negative impact on healthcare systems, which were not used to coping with such pandemic. Adaptation strategies prioritizing COVID-19 patients included triage of patients and reduction or re-allocation of other services. The aim of our survey was to provide a real time international snapshot of modifications of breast cancer...

Université de Fribourg

Magi1, a new potential tumor suppressor gene in estrogen receptor positive breast cancer

Alday-Parejo, Begoña ; Richard, François ; Wörthmüller, Janine ; Rau, Tilman ; Galván, José A. ; Desmedt, Christine ; Santamaria-Martinez, Albert ; Rüegg, Curzio

In: Cancers, 2020, vol. 12, no. 1, p. 223

Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an intracellular adaptor protein that stabilizes epithelial junctions consistent with a tumor suppressive function in several cancers of epithelial origin. Here we report, based on experimental results and human breast cancer (BC) patients’ gene expression data, that MAGI1 is highly expressed and acts...

Université de Fribourg

Detection of HER2+ breast cancer cells using bioinspired DNA-based signal amplification

Rafiee, Sarah D. ; Kocabey, Samet ; Mayer, Michael ; List, Jonathan ; Rüegg, Curzio

In: ChemMedChem, 2020, vol. 15, no. 8, p. 661-666

Circulating tumor cells (CTC) are promising biomarkers for metastatic cancer detection and monitoring progression. However, detection of CTCs remains challenging due to their low frequency and heterogeneity. Herein, we report a bioinspired approach to detect individual cancer cells, based on a signal amplification cascade using a programmable DNA hybridization chain reaction (HCR) circuit. We...

Consortium of Swiss Academic Libraries

Effect of aflibercept in insufficient responders to prior anti-VEGF therapy in neovascular AMD

Fassnacht-Riederle, Heidi ; Becker, Matthias ; Graf, Nicole ; Michels, Stephan

In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2014, vol. 252, no. 11, p. 1705-1709