In: Angiogenesis, 2015, vol. 18, no. 3, p. 233-244
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In: Clinical & Experimental Metastasis, 2015, vol. 32, no. 7, p. 677-687
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In: European Archives of Oto-Rhino-Laryngology, 2015, vol. 272, no. 7, p. 1725-1731
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In: Interactive CardioVascular and Thoracic Surgery, 2016, vol. 22, no. 5, p. 647-662
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In: Analytical and Bioanalytical Chemistry, 2015, vol. 407, no. 21, p. 6237-6255
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In: Leukemia, 2021, p. 7 p
The prognostic significance of lymphocyte doubling time (LDT) in chronic lymphocytic leukemia (CLL) was identified when the biology of the disease was poorly understood and therapy was not effective. We assessed the clinical and biological significance of LDT in 848 CLL patients in a real-life setting and the context of new biomarkers and effective therapy. A short LDT (≤12 months) was...
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In: Blood, 2020, vol. 137, no. 10, p. 1365–1376
Chronic lymphocytic leukemia (CLL) is characterized by the existence of subsets of patients with (quasi)identical, stereotyped B cell receptor immunoglobulins (BcR IG). Patients in certain major stereotyped subsets often display remarkably consistent clinicobiological profiles, suggesting that the study of BcR IG stereotypy in CLL has important implications for understanding disease...
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In: Blood, 2020, vol. 135, no. 21, p. 1859–1869
Most patients with chronic lymphocytic leukemia (CLL) are diagnosed with early-stage disease and managed with active surveillance. The individual course of patients with early-stage CLL is heterogeneous, and their probability of needing treatment is hardly anticipated at diagnosis. We aimed at developing an international prognostic score to predict time to first treatment (TTFT) in patients...
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In: Science Immunology, 2020, vol. 5, no. 46, p. eaaz4371
It is well established that tissue macrophages and tissue-resident memory CD8+ T cells (TRM) play important roles for pathogen sensing and rapid protection of barrier tissues. In contrast, the mechanisms by which these two cell types cooperate for homeostatic organ surveillance after clearance of infections is poorly understood. Here, we used intravital imaging to show that TRM dynamically...
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In: BioScience, 2019, vol. 69, no. 11, p. 908–919
For many species, human-induced environmental changes are important indirect drivers of range expansion into new regions. We argue that it is important to distinguish the range dynamics of such species from those that occur without, or with less clear, involvement of human-induced environmental changes. We elucidate the salient features of the rapid increase in the number of species whose...
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