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Consortium of Swiss Academic Libraries

Depression as a risk factor for acute coronary syndrome: a review

Misteli, Genny ; Stute, Petra

In: Archives of Gynecology and Obstetrics, 2015, vol. 291, no. 6, p. 1213-1220

Université de Fribourg

Multiple cryoinjuries modulate the efficiency of zebrafish heart regeneration

Bise, Thomas ; Sallin, Pauline ; Pfefferli, Catherine ; Jaźwińska, Anna

In: Scientific Reports, 2020, vol. 10, no. 1, p. 11551

Zebrafish can regenerate their damaged hearts throughout their lifespan. It is, however, unknown, whether regeneration remains effective when challenged with successive cycles of cardiac damage in the same animals. Here, we assessed ventricular restoration after two, three and six cryoinjuries interspaced by recovery periods. Using transgenic cell-lineage tracing analysis, we demonstrated...

Université de Fribourg

Role of extracellular vesicles in cellular cross talk in malaria

Babatunde, Kehinde Adebayo ; Subramanian, Bibin Yesodha ; Ahouidi, Ambroise Dioum ; Murillo, Paola Martinez ; Walch, Michael

In: Frontiers in Immunology, 2020, vol. 11, p. -

Malaria infection caused by the Plasmodium species is a complex disease in which a fine balance between host and parasite factors determine the outcome of the disease. While in some individuals, the infection will trigger only a mild and uncomplicated disease, other individuals will develop severe complications and eventually die. Extracellular vesicles (EVs) secreted by infected red blood...

Université de Fribourg

Human microglia respond to malaria-induced extracellular vesicles

Mbagwu, Smart Ikechukwu ; Lannes, Nils ; Walch, Michael ; Filgueira, Luis ; Mantel, Pierre-Yves

In: Pathogens, 2020, vol. 9, no. 1, p. 21

Microglia are the chief immune cells of the brain and have been reported to be activated in severe malaria. Their activation may drive towards neuroinflammation in cerebral malaria. Malaria-infected red blood cell derived-extracellular vesicles (MiREVs) are produced during the blood stage of malaria infection. They mediate intercellular communication and immune regulation, among other...