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Increased periodontal inflammation in women with preterm premature rupture of membranes

Stadelmann, Pascale ; Eick, Sigrun ; Salvi, Giovanni ; Surbek, Daniel ; Mohr, Stefan ; Bürgin, Walter ; Ramseier, Christoph ; Sculean, Anton

In: Clinical Oral Investigations, 2015, vol. 19, no. 6, p. 1537-1546

N -methyl pyrrolidone (NMP) inhibits lipopolysaccharide-induced inflammation by suppressing NF-κB signaling

Ghayor, Chafik ; Gjoksi, Bebeka ; Siegenthaler, Barbara ; Weber, Franz

In: Inflammation Research, 2015, vol. 64, no. 7, p. 527-536

Molecular and cellular basis of bone resorption = Anatomy and biochemistry of the osteoclast

Gruber, Reinhard

In: Wiener Medizinische Wochenschrift, 2015, vol. 165, no. 3-4, p. 48-53

Parasites suppress immune-enhancing effect of methionine in nestling great tits

Wegmann, Michèle ; Voegeli, Beatrice ; Richner, Heinz

In: Oecologia, 2015, vol. 177, no. 1, p. 213-221

Oral lichen planus (OLP), oral lichenoid lesions (OLL), oral dysplasia, and oral cancer: retrospective analysis of clinicopathological data from 2002-2011

Casparis, S. ; Borm, J. ; Tektas, S. ; Kamarachev, J. ; Locher, M. ; Damerau, G. ; Grätz, K. ; Stadlinger, B.

In: Oral and Maxillofacial Surgery, 2015, vol. 19, no. 2, p. 149-156

FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase

Imeri, Faik ; Blanchard, Olivier ; Jenni, Aurelio ; Schwalm, Stephanie ; Wünsche, Christin ; Zivkovic, Aleksandra ; Stark, Holger ; Pfeilschifter, Josef ; Huwiler, Andrea

In: Naunyn-Schmiedeberg's Archives of Pharmacology, 2015, vol. 388, no. 12, p. 1283-1292

Sterile-filtered saliva is a strong inducer of IL-6 and IL-8 in oral fibroblasts

Cvikl, Barbara ; Lussi, Adrian ; Moritz, Andreas ; Sculean, Anton ; Gruber, Reinhard

In: Clinical Oral Investigations, 2015, vol. 19, no. 2, p. 385-399

Increased uptake of silica nanoparticles in inflamed macrophages but not upon co-exposure to micron-sized particles

Susnik, Eva ; Taladriz-Blanco, Patricia ; Drasler, Barbara ; Balog, Sandor ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Cells, 2020, vol. 9, no. 9, p. 2099

Silica nanoparticles (NPs) are widely used in various industrial and biomedical applications. Little is known about the cellular uptake of co-exposed silica particles, as can be expected in our daily life. In addition, an inflamed microenvironment might affect a NP’s uptake and a cell’s physiological response. Herein, prestimulated mouse J774A.1 macrophages with bacterial...

An inflamed human alveolar model for testing the efficiency of anti-inflammatory drugs in vitro

Drasler, Barbara ; Karakocak, Bedia Begum ; Tankus, Esma Bahar ; Barosova, Hana ; Abe, Jun ; Sousa de Almeida, Mauro ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Frontiers in Bioengineering and Biotechnology, 2020, vol. 8, p. -

A large number of prevalent lung diseases is associated with tissue inflammation. Clinically, corticosteroid therapies are applied systemically or via inhalation for the treatment of lung inflammation, and a number of novel therapies are being developed that require preclinical testing. In alveoli, macrophages and dendritic cells play a key role in initiating and diminishing pro-inflammatory...

Macrophage death following influenza vaccination initiates the inflammatory response that promotes dendritic cell function in the draining lymph node

Chatziandreou, Nikolaos ; Farsakoglu, Yagmur ; Palomino-Segura, Miguel ; D’Antuono, Rocco ; Pizzagalli, Diego Ulisse ; Sallusto, Federica ; Lukacs-Kornek, Veronika ; Uguccioni, Mariagrazia ; Corti, Davide ; Turley, Shannon J. ; Lanzavecchia, Antonio ; Carroll, Michael C. ; Gonzalez, Santiago F.

In: Cell reports, 2017, vol. 18, no. 10, p. 2427-2440

The mechanism by which inflammation influences the adaptive response to vaccines is not fully understood. Here, we examine the role of lymph node macrophages (LNMs) in the induction of the cytokine storm triggered by inactivated influenza virus vaccine. Following vaccination, LNMs undergo inflammasome-independent necrosis-like death that is reliant on MyD88 and Toll-like receptor 7 (TLR7)...