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Autoimmmune hepatitis

Terziroli Beretta-Piccoli, Benedetta ; Mieli Vergani, Giorgina ; Vergani, Diego

In: Cellular & molecular immunology, 2021, p. 19

Autoimmune hepatitis (AIH) is a T-cell mediated, inflammatory liver disease affecting all ages and characterized by female preponderance, elevated serum transaminase and immunoglobulin G levels, positive circulating autoantibodies, and presence of interface hepatitis at liver histology. AIH type 1, affecting both adults and children, is defined by positive anti- nuclear and/or antismooth muscle...

Cobicistat versus ritonavir boosting and differences in the drug-drug interaction profiles with co-medications

Marzolini, Catia ; Gibbons, Sara ; Khoo, Saye ; Back, David

In: Journal of Antimicrobial Chemotherapy, 2016, vol. 71, no. 7, p. 1755-1758

Vitamin D-Dependent Rickets Type 1 Caused by Mutations in CYP27B1 Affecting Protein Interactions With Adrenodoxin

Zalewski, Adam ; Ma, Nina S. ; Legeza, Balazs ; Renthal, Nora ; Flück, Christa E. ; Pandey, Amit V.

In: The Journal of Clinical Endocrinology & Metabolism, 2016, vol. 101, no. 9, p. 3409-3418

Quantitative monitoring of tamoxifen in human plasma extended to 40 metabolites using liquid-chromatography high-resolution mass spectrometry: new investigation capabilities for clinical pharmacology

Dahmane, Elyes ; Boccard, Julien ; Csajka, Chantal ; Rudaz, Serge ; Décosterd, Laurent ; Genin, Eric ; Duretz, Bénédicte ; Bromirski, Maciej ; Zaman, Khalil ; Testa, Bernard ; Rochat, Bertrand

In: Analytical and Bioanalytical Chemistry, 2014, vol. 406, no. 11, p. 2627-2640

Phenotyping of CYP450 in human liver microsomes using the cocktail approach

Spaggiari, Dany ; Geiser, Laurent ; Daali, Youssef ; Rudaz, Serge

In: Analytical and Bioanalytical Chemistry, 2014, vol. 406, no. 20, p. 4875-4887

Impact of variable CYP genotypes on breast cancer relapse in patients undergoing adjuvant tamoxifen therapy

Mwinyi, Jessica ; Vokinger, Kerstin ; Jetter, Alexander ; Breitenstein, Urs ; Hiller, Christian ; Kullak-Ublick, Gerd ; Trojan, Andreas

In: Cancer Chemotherapy and Pharmacology, 2014, vol. 73, no. 6, p. 1181-1188

New trends in fast and high-resolution liquid chromatography: a critical comparison of existing approaches

Guillarme, Davy ; Ruta, Josephine ; Rudaz, Serge ; Veuthey, Jean-Luc

In: Analytical and Bioanalytical Chemistry, 2010, vol. 397, no. 3, p. 1069-1082

Identification of a CYP3A form (CYP3A126) in fathead minnow ( Pimephales promelas ) and characterisation of putative CYP3A enzyme activity

Christen, Verena ; Caminada, Daniel ; Arand, Michael ; Fent, Karl

In: Analytical and Bioanalytical Chemistry, 2010, vol. 396, no. 2, p. 585-595

Genetic polymorphism and drug interactions: their importance in the treatment of pain = Polymorphisme génétique et interactions médicamenteuses : leur importance dans le traitement de la douleur

Samer, Caroline ; Piguet, Valérie ; Dayer, Pierre ; Desmeules, Jules

In: Canadian Journal of Anesthesia, 2005, vol. 52, no. 8, p. 806-821

High-resolution mass spectrometry for integrated qualitative and quantitative analysis of pharmaceuticals in biological matrices

Hopfgartner, Gérard ; Tonoli, David ; Varesio, Emmanuel

In: Analytical and Bioanalytical Chemistry, 2012, vol. 402, no. 8, p. 2587-2596