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Low-grade inflammation and tryptophan-kynurenine pathway activation are associated with adverse cardiac remodeling in primary hyperparathyroidism: the EPATH trial

Verheyen, Nicolas ; Meinitzer, Andreas ; Grübler, Martin Robert ; Ablasser, Klemens ; Kolesnik, Ewald ; Fahrleitner-Pammer, Astrid ; Belyavskiy, Evgeny ; Trummer, Christian ; Schwetz, Verena ; Pieske-Kraigher, Elisabeth ; Voelkl, Jakob ; Alesutan, Ioana ; Catena, Cristiana ; Sechi, Leonardo Alberto ; Brussee, Helmut ; Lewinski, Dirk von ; März, Winfried ; Pieske, Burkert ; Pilz, Stefan ; Tomaschitz, Andreas

In: Clinical Chemistry and Laboratory Medicine (CCLM), 2017, vol. 55, no. 7, p. 1034-1042

Associations of Serum 25-Hydroxyvitamin D With Hemostatic and Inflammatory Biomarkers in the Multi-Ethnic Study of Atherosclerosis

Blondon, Marc ; Cushman, Mary ; Jenny, Nancy ; Michos, Erin D. ; Smith, Nicholas L. ; Kestenbaum, Bryan ; de Boer, Ian H.

In: The Journal of Clinical Endocrinology & Metabolism, 2016, vol. 101, no. 6, p. 2348-2357

The intestinal microbiota: its role in health and disease

Biedermann, Luc ; Rogler, Gerhard

In: European Journal of Pediatrics, 2015, vol. 174, no. 2, p. 151-167

Socio-economic trajectories and cardiovascular disease mortality in older people: the English Longitudinal Study of Ageing

Stringhini, Silvia ; Zaninotto, Paola ; Kumari, Meena ; Kivimäki, Mika ; Lassale, Camille ; Batty, G David

In: International Journal of Epidemiology, 2018, vol. 47, no. 1, p. 36-46

Whole-body MRI in adult inflammatory myopathies: Do we need imaging of the trunk?

Filli, Lukas ; Maurer, Britta ; Manoliu, Andrei ; Andreisek, Gustav ; Guggenberger, Roman

In: European Radiology, 2015, vol. 25, no. 12, p. 3499-3507

Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

Blum, Manuel R. ; Gencer, Baris ; Adam, Luise ; Feller, Martin ; Collet, Tinh-Hai ; da Costa, Bruno R. ; Moutzouri, Elisavet ; Dopheide, Jörn ; Depairon, Michèle ; Sykiotis, Gerasimos P. ; Kearney, Patricia ; Gussekloo, Jacobijn ; Westendorp, Rudi ; Stott, David J. ; Bauer, Douglas C. ; Rodondi, Nicolas

In: The Journal of Clinical Endocrinology & Metabolism, 2018, vol. 103, no. 8, p. 2988-2997

Plasma levels of endothelin-1 and renal function among young and healthy adults

Fischer, Andreas ; Bossard, Matthias ; Aeschbacher, Stefanie ; Egli, Peter ; Cordewener, Carolin ; Estis, Joel ; Todd, John ; Risch, Martin ; Risch, Lorenz ; Conen, David

In: Clinical Chemistry and Laboratory Medicine (CCLM), 2017, vol. 55, no. 8, p. 1202-1208

Serum cholesterol acceptor capacity in intrauterine growth restricted fetuses

Pecks, Ulrich ; Rath, Werner ; Bauerschlag, Dirk O. ; Maass, Nicolai ; Orlikowsky, Thorsten ; Mohaupt, Markus G. ; Escher, Geneviève

In: Journal of Perinatal Medicine, 2017, vol. 45, no. 7, p. 829-835

An inflamed human alveolar model for testing the efficiency of anti-inflammatory drugs in vitro

Drasler, Barbara ; Karakocak, Bedia Begum ; Tankus, Esma Bahar ; Barosova, Hana ; Abe, Jun ; Sousa de Almeida, Mauro ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Frontiers in Bioengineering and Biotechnology, 2020, vol. 8, p. -

A large number of prevalent lung diseases is associated with tissue inflammation. Clinically, corticosteroid therapies are applied systemically or via inhalation for the treatment of lung inflammation, and a number of novel therapies are being developed that require preclinical testing. In alveoli, macrophages and dendritic cells play a key role in initiating and diminishing pro-inflammatory...

Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis

Hu, Dan ; Notarbartolo, Samuele ; Croonenborghs, Tom ; Patel, Bonny ; Cialic, Ron ; Yang, Tun-Hsiang ; Aschenbrenner, Dominik ; Andersson, Karin M. ; Gattorno, Marco ; Pham, Minh ; Kivisakk, Pia ; Pierre, Isabelle V. ; Lee, Youjin ; Kiani, Karun ; Bokarewa, Maria ; Tjon, Emily ; Pochet, Nathalie ; Sallusto, Federica ; Kuchroo, Vijay K. ; Weiner, Howard L.

In: Nature communications, 2017, vol. 8, p. 1600

We have previously reported the molecular signature of murine pathogenic TH17 cells that induce experimental autoimmune encephalomyelitis (EAE) in animals. Here we show that human peripheral blood IFN-γ+IL-17+ (TH1/17) and IFN-γ−IL-17+ (TH17) CD4+ T cells display distinct transcriptional profiles in high-throughput transcription analyses. Compared to TH17 cells, TH1/17 cells have gene...