In: Journal of Neurology, 2021, no. 268, p. 817–824
Background: Data on cancer prevalence and incidence in multiple sclerosis (MS) patients are controversial. This study is aimed at estimating cancer risk in MS patients. Methods: Nested case–control study using data collected between 01/01/1987 and 28/02/2016 from the United Kingdom Clinical Practice Research Datalink. Cancer diagnoses after first MS code (index date) was counted in 10,204 MS...
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In: Antibiotics, 2021, vol. 10, no. 2, p. 9
Aminoglycoside or colistin therapy may alter the renal tubular function without decreasing the glomerular filtration rate. This association has never been extensively investigated. We conducted a systematic review of the literature following the Preferred Reporting Items for Systematic Reviews and Meta- Analyses recommendations. Databases searched included United States National Library of...
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In: World Journal of Surgery, 2015, vol. 39, no. 7, p. 1767-1772
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In: International Journal of Neuropsychopharmacology, 2016, vol. 19, no. 1, p. -
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In: Blood, 2020, vol. 135, no. 21, p. 1859–1869
Most patients with chronic lymphocytic leukemia (CLL) are diagnosed with early-stage disease and managed with active surveillance. The individual course of patients with early-stage CLL is heterogeneous, and their probability of needing treatment is hardly anticipated at diagnosis. We aimed at developing an international prognostic score to predict time to first treatment (TTFT) in patients...
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In: Pediatric Nephrology, 2014, vol. 29, no. 6, p. 1015-1023
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In: European Journal of Clinical Pharmacology, 2014, vol. 70, no. 7, p. 829-837
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In: Radiochimica Acta, 2016, vol. 104, no. 11, p. 769-779
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In: Cancer Chemotherapy and Pharmacology, 2014, vol. 74, no. 6, p. 1307-1319
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In: Proceedings of the national academy of sciences, 2017, vol. 114, no. 8, p. E1490-E1499
DNA methylation and specifically the DNA methyltransferase enzyme DNMT3A are involved in the pathogenesis of a variety of hematological diseases and in regulating the function of immune cells. Although altered DNA methylation patterns and mutations in DNMT3A correlate with mast cell proliferative disorders in humans, the role of DNA methylation in mast cell biology is not understood. By using...
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