In: Interchange, 2015, vol. 46, no. 4, p. 313-321
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In: Mathematical Programming, 2015, vol. 154, no. 1-2, p. 427-462
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In: PLOS Computational Biology, 2019, vol. 15, no. 4, p. e1006946
Bacterial Toxin-Antitoxin systems (TAS) are involved in key biological functions including plasmid maintenance, defense against phages, persistence and virulence. They are found in nearly all phyla and classified into 6 different types based on the mode of inactivation of the toxin, with the type II TAS being the best characterized so far. We have herein developed a new in silico discovery...
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