A three-dimensional in vitro dynamic micro-tissue model of cardiac scar formation
Occhetta, Paola ; Isu, Giuseppe ; Lemme, Marta ; Conficconi, Chiara ; Oertle, Philipp ; Räz, Christian ; Visone, Roberta ; Cerino, Giulia ; Plodinec, Marija ; Rasponi, Marco ; Marsano, Anna
In: Integrative Biology, 2018, vol. 10, no. 3, p. 174-183
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- Our 3D-scar-on-a-chip model resembles fibroblast proliferation and activation, extracellular matrix deposition and stiffening upon application of only cyclic mechanical stretching.