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Image quality of low mA CT pulmonary angiography reconstructed with model based iterative reconstruction versus standard CT pulmonary angiography reconstructed with filtered back projection: an equivalency trial

Montet, Xavier ; Hachulla, Anne-Lise ; Neroladaki, Angeliki ; Lador, Frederic ; Rochat, Thierry ; Botsikas, Diomidis ; Becker, Christoph

In: European Radiology, 2015, vol. 25, no. 6, p. 1665-1671

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    Titre
    • Image quality of low mA CT pulmonary angiography reconstructed with model based iterative reconstruction versus standard CT pulmonary angiography reconstructed with filtered back projection: an equivalency trial
    Auteur
    • Montet, Xavier. Division of Radiology, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211, Geneva 4, Switzerland
    • Hachulla, Anne-Lise. Division of Radiology, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211, Geneva 4, Switzerland
    • Neroladaki, Angeliki. Division of Radiology, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211, Geneva 4, Switzerland
    • Lador, Frederic. Division of Pulmonary Medicine, Geneva University Hospital, Gabrielle-Perret-Gentil, 4, 1211, Geneva 4, Switzerland
    • Rochat, Thierry. Division of Pulmonary Medicine, Geneva University Hospital, Gabrielle-Perret-Gentil, 4, 1211, Geneva 4, Switzerland
    • Botsikas, Diomidis. Division of Radiology, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211, Geneva 4, Switzerland
    • Becker, Christoph. Division of Radiology, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211, Geneva 4, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • European Radiology, 2015, vol. 25, no. 6, p. 1665-1671. Springer Berlin Heidelberg
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:331671
    Summary
    Objective: To determine whether CT pulmonary angiography (CTPA) using low mA setting reconstructed with model-based iterative reconstruction (MBIR) is equivalent to routine CTPA reconstructed with filtered back projection (FBP). Methods: This prospective study was approved by the institutional review board and patients provided written informed consent. Eighty-two patients were examined with a low mA MBIR-CTPA (100kV, 20mA) and 82 patients with a standard FBP-CTPA (100kV, 250mA). Region of interests were drawn in nine pulmonary vessels; signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. A five-point scale was used to subjectively evaluate the image quality of FBP-CTPA and low mA MBIR-CTPA. Results: Compared to routine FBP-CTPA, low mA MBIR-CTPA showed no differences in the attenuation measured in nine pulmonary vessels, higher SNR (56 ± 19 vs 43 ± 20, p < 0.0001) and higher CNR (50 ± 17 vs 38 ± 18, p < 0.0001) despite a dose reduction of 93% (p < 0.0001). The subjective image quality of low mA MBIR-CTPA was quoted as diagnostic in 98% of the cases for patient with body mass index less than 30kg/m2. Conclusion: Low mA MBIR-CTPA is equivalent to routine FBP-CTPA and allows a significant dose reduction while improving SNR and CNR in the pulmonary vessels, as compared with routine FBP-CTPA. Key Points : • Low mA MBIR-CTPA is equivalent to routine FBP-CTPA. • MBIR-CTPA may be achieved with drastic (93%) dose reduction. • Low mA MBIR-CTPA should be studied in the setting of suspected PE.