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Simultaneous measurement of the maximum oscillation amplitude and the transient decay time constant of the QCM reveals stiffness changes of the adlayer

Marxer, C. ; Coen, M. ; Bissig, H. ; Greber, U. ; Schlapbach, L.

In: Analytical and Bioanalytical Chemistry, 2003, vol. 377, no. 3, p. 570-577

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    Titel
    • Simultaneous measurement of the maximum oscillation amplitude and the transient decay time constant of the QCM reveals stiffness changes of the adlayer
    Autor
    • Marxer, C.. Solid State Physics Research Group, University of Fribourg, Pérolles, 1700, Fribourg, Switzerland
    • Coen, M.. Solid State Physics Research Group, University of Fribourg, Pérolles, 1700, Fribourg, Switzerland
    • Bissig, H.. Soft Condensed Matter Physics Group, University of Fribourg, Pérolles, 1700, Fribourg, Switzerland
    • Greber, U.. Institute of Zoology, University of Zürich, Winterthurerstrasse 190, 8057, Zürich, Switzerland
    • Schlapbach, L.. Solid State Physics Research Group, University of Fribourg, Pérolles, 1700, Fribourg, Switzerland
    Dokumententyp
    • Postprint
    Sprache
    • Englisch
    Veröffentlicht in
    • Analytical and Bioanalytical Chemistry, 2003, vol. 377, no. 3, p. 570-577. Springer-Verlag
    Andere elektronische Ausgabe
    OAI-PMH-ID
    • oai:doc.rero.ch:322249
    Summary
    Interpretation of adsorption kinetics measured with a quartz crystal microbalance (QCM) can be difficult for adlayers undergoing modification of their mechanical properties. We have studied the behavior of the oscillation amplitude, A 0, and the decay time constant, τ, of quartz during adsorption of proteins and cells, by use of a home-made QCM. We are able to measure simultaneously the frequency, f, the dissipation factor, D, the maximum amplitude, A 0, and the transient decay time constant, τ, every 300ms in liquid, gaseous, or vacuum environments. This analysis enables adsorption and modification of liquid/mass properties to be distinguished. Moreover the surface coverage and the stiffness of the adlayer can be estimated. These improvements promise to increase the appeal of QCM methodology for any applications measuring intimate contact of a dynamic material with a solid surface