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Bmi1 in development and tumorigenesis of the central nervous system

Shakhova, Olga ; Leung, Carly ; Marino, Silvia

In: Journal of Molecular Medicine, 2005, vol. 83, no. 8, p. 596-600

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    Titre
    • Bmi1 in development and tumorigenesis of the central nervous system
    Auteur
    • Shakhova, Olga. Institute of Clinical Pathology, University Hospital, Schmelzbergstrasse 12, 8091, Zürich, Switzerland
    • Leung, Carly. Institute of Clinical Pathology, University Hospital, Schmelzbergstrasse 12, 8091, Zürich, Switzerland
    • Marino, Silvia. Institute of Clinical Pathology, University Hospital, Schmelzbergstrasse 12, 8091, Zürich, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Journal of Molecular Medicine, 2005, vol. 83, no. 8, p. 596-600. Springer-Verlag; http://www.springer.de
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:320794
    Summary
    The role of the Polycomb group gene Bmi1 in proliferation control of lymphoid and neuronal progenitors as well as in self-renewal of haematopoietic and neural stem cells has been recently demonstrated. Here we review these recent findings with particular regard to their implications for central nervous system development and tumorigenesis