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C-arm flat-panel CT arthrography of the wrist and elbow: first experiences in human cadavers

Guggenberger, Roman ; Morsbach, Fabian ; Alkadhi, Hatem ; Vich, Magdalena ; Pfammatter, Thomas ; Hodler, Juerg ; Andreisek, Gustav

In: Skeletal Radiology, 2013, vol. 42, no. 3, p. 419-429

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    Titre
    • C-arm flat-panel CT arthrography of the wrist and elbow: first experiences in human cadavers
    Auteur
    • Guggenberger, Roman. Department of Radiology, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland
    • Morsbach, Fabian. Department of Radiology, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland
    • Alkadhi, Hatem. Department of Radiology, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland
    • Vich, Magdalena. Institute of Anatomy, University Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland
    • Pfammatter, Thomas. Department of Radiology, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland
    • Hodler, Juerg. Department of Radiology, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland
    • Andreisek, Gustav. Department of Radiology, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland
    Type de document
    • Postprint
    Identifiant OAI-PMH
    • oai:doc.rero.ch:320094
    Summary
    Objective: To determine the optimal intra-articular iodine concentration for C-arm flat-panel computed tomography (FPCT) arthrography using advanced joint phantoms and to evaluate its application in human cadaveric wrists and elbows. Multi-detector (MD) CT served as the standard of reference. Materials and methods: Joint phantoms and 10 human cadaveric wrist and elbow joints were scanned with C-arm FPCT (5-s, 8-s, and 20-s runs) and standard MDCT using different and optimal concentrations of iodinated contrast material. CT numbers of contrast material, tissue, and noise were measured and contrast-to-noise ratios (CNR) calculated for quantitative analysis. Image and depiction of cartilage, bone, and soft tissues were rated. Radiation doses were compared. Results: In FPCT, iodine concentrations positively correlated with CT numbers and noise of contrast material and with radiation dose (r = 0.713-0.996, p < 0.05 each). At an iodine concentration of 45mg/ml, CNR of cartilage and soft tissues were highest for all FPCT acquisitions and higher than in MDCT. The 20-s FPCT run performed best for image quality and depiction of anatomical structures and was rated overall equal to MDCT (p = 0.857). Conclusion: The optimal iodine concentration for C-arm FPCT arthrography in this study is 45mg/ml, leading to superior CNR and image quality for an optimal FPCT protocol compared with standard MDCT arthrography in human cadaveric joints