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What can we learn from ambient ionization techniques?

Chen, Huanwen ; Gamez, Gerardo ; Zenobi, Renato

In: Journal of the American Society for Mass Spectrometry, 2009, vol. 20, no. 11, p. 1947-1963

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    Titre
    • What can we learn from ambient ionization techniques?
    Auteur
    • Chen, Huanwen. Applied Chemistry Department, East China Institute of Technology, Fuzhou, China
    • Gamez, Gerardo. Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093, Zürich, Switzerland
    • Zenobi, Renato. Department of Chemistry and Applied Biosciences, ETH Zürich, CH-8093, Zürich, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Journal of the American Society for Mass Spectrometry, 2009, vol. 20, no. 11, p. 1947-1963. Springer-Verlag
    Autre version électronique
    Classification
    • Chimie
    Identifiant OAI-PMH
    • oai:doc.rero.ch:312274
    Summary
    Ambient mass spectrometry—mass spectrometric analysis with no or minimal effort for sample preparation—has experienced a very rapid development during the last 5 years, with many different methods now available for ionization. Here, we review its range of applications, the hurdles encountered for its quantitative use, and the proposed mechanisms for ion formation. Clearly, more effort needs to be put into investigation of matrix effects, into defining representative sampling of heterogeneous materials, and into understanding and controlling the underlying ionization mechanisms. Finally, we propose a concept to reduce the number of different acronyms describing very similar embodiments of ambient mass spectrometry