Single breath-hold slice-following CSPAMM myocardial tagging
Stuber, M. ; Spiegel, M. ; Fischer, S. ; Scheidegger, M. ; Danias, P. ; Pedersen, E. ; Boesiger, P.
In: Magnetic Resonance Materials in Physics, Biology and Medicine, 1999, vol. 9, no. 1-2, p. 85-91
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- Myocardial tagging has shown to be a useful magnetic resonance modality for the assessment and quantification of local myocardial function. Many myocardial tagging techniques suffer from a rapid fading of the tags, restricting their application mainly to systolic phases of the cardiac cycle. However, left ventricular diastolic dysfunction has been increasingly appreciated as a major cause of heart failure. Subtraction based slice-following CSPAMM myocardial tagging has shown to overcome limitations such as fading of the tags. Remaining impediments, to this technique, however, are extensive scanning times (∼10 min), the requirement of repeated breath-holds using a coached breathing pattern, and the enhanced sensitivity of artifacts related to poor patient compliance or inconsistent depths of end-expiratory breath-holds. We therefore propose a combination of slice-following CSPAMM myocardial tagging with a segmented EPI imaging sequence. Together with an optimized RF excitation scheme, this enables to acquire as many as 20 systolic and diastolic grid-tagged images per cardiac cycle with a high tagging contrast during a short period of sustained respiration