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Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons

Rotger, Margalida ; Glass, Tracy R. ; Junier, Thomas ; Lundgren, Jens ; Neaton, James D. ; Poloni, Estella S. ; van 't Wout, Angélique B. ; Lubomirov, Rubin ; Colombo, Sara ; Martinez, Raquel ; Rauch, Andri ; Günthard, Huldrych F. ; Neuhaus, Jacqueline ; Wentworth, Deborah ; van Manen, Danielle ; Gras, Luuk A. ; Schuitemaker, Hanneke ; Albini, Laura ; Torti, Carlo ; Jacobson, Lisa P. ; Li, Xiuhong ; Kingsley, Lawrence A. ; Carli, Federica ; Guaraldi, Giovanni ; Ford, Emily S. ; Sereti, Irini ; Hadigan, Colleen ; Martinez, Esteban ; Arnedo, Mireia ; Egaña-Gorroño, Lander ; Gatell, Jose M. ; Law, Matthew ; Bendall, Courtney ; Petoumenos, Kathy ; Rockstroh, Jürgen ; Wasmuth, Jan-Christian ; Kabamba, Kabeya ; Delforge, Marc ; De Wit, Stephane ; Berger, Florian ; Mauss, Stefan ; de Paz Sierra, Mariana ; Losso, Marcelo ; Belloso, Waldo H. ; Leyes, Maria ; Campins, Antoni ; Mondi, Annalisa ; De Luca, Andrea ; Bernardino, Ignacio ; Barriuso-Iglesias, Mónica ; Torrecilla-Rodriguez, Ana ; Gonzalez-Garcia, Juan ; Arribas, José R. ; Fanti, Iuri ; Gel, Silvia ; Puig, Jordi ; Negredo, Eugenia ; Gutierrez, Mar ; Domingo, Pere ; Fischer, Julia ; Fätkenheuer, Gerd ; Alonso-Villaverde, Carlos ; Macken, Alan ; Woo, James ; McGinty, Tara ; Mallon, Patrick ; Mangili, Alexandra ; Skinner, Sally ; Wanke, Christine A. ; Reiss, Peter ; Weber, Rainer ; Bucher, Heiner C. ; Fellay, Jacques ; Telenti, Amalio ; Tarr, Philip E.

In: Clinical Infectious Diseases, 2013, vol. 57, no. 1, p. 112-121

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    Title
    • Contribution of Genetic Background, Traditional Risk Factors, and HIV-Related Factors to Coronary Artery Disease Events in HIV-Positive Persons
    Author
    • Rotger, Margalida. Institute of Microbiology, University Hospital Center, University of Lausanne
    • Glass, Tracy R.. Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel
    • Junier, Thomas. Swiss Institute of Bioinformatics, Lausanne, and
    • Lundgren, Jens. International Network for Strategic Initiatives in Global HIV Trials
    • Neaton, James D.. International Network for Strategic Initiatives in Global HIV Trials
    • Poloni, Estella S.. Laboratory of Anthropology, Department of Genetics and Evolution, University of Geneva
    • van 't Wout, Angélique B.. AIDS Therapy Evaluation in the Netherlands, Amsterdam
    • Lubomirov, Rubin. Institute of Microbiology, University Hospital Center, University of Lausanne
    • Colombo, Sara. Institute of Microbiology, University Hospital Center, University of Lausanne
    • Martinez, Raquel. Institute of Microbiology, University Hospital Center, University of Lausanne
    • Rauch, Andri. Swiss HIV Cohort Study
    • Günthard, Huldrych F.. Swiss HIV Cohort Study
    • Neuhaus, Jacqueline. International Network for Strategic Initiatives in Global HIV Trials
    • Wentworth, Deborah. International Network for Strategic Initiatives in Global HIV Trials
    • van Manen, Danielle. AIDS Therapy Evaluation in the Netherlands, Amsterdam
    • Gras, Luuk A.. AIDS Therapy Evaluation in the Netherlands, Amsterdam
    • Schuitemaker, Hanneke. AIDS Therapy Evaluation in the Netherlands, Amsterdam
    • Albini, Laura. Department of Infectious Diseases, University of Brescia
    • Torti, Carlo. Department of Infectious Diseases, University of Brescia
    • Jacobson, Lisa P.. Multicenter AIDS Cohort Study
    • Li, Xiuhong. Multicenter AIDS Cohort Study
    • Kingsley, Lawrence A.. Multicenter AIDS Cohort Study
    • Carli, Federica. University of Modena and Reggio Emilia, Italy
    • Guaraldi, Giovanni. University of Modena and Reggio Emilia, Italy
    • Ford, Emily S.. Intramural National Institute of Allergy and Infectious Diseases Cohort, Bethesda, Maryland
    • Sereti, Irini. Intramural National Institute of Allergy and Infectious Diseases Cohort, Bethesda, Maryland
    • Hadigan, Colleen. Intramural National Institute of Allergy and Infectious Diseases Cohort, Bethesda, Maryland
    • Martinez, Esteban. Hospital Clinic-IDIBAPS, Barcelona, Spain
    • Arnedo, Mireia. Hospital Clinic-IDIBAPS, Barcelona, Spain
    • Egaña-Gorroño, Lander. Hospital Clinic-IDIBAPS, Barcelona, Spain
    • Gatell, Jose M.. Hospital Clinic-IDIBAPS, Barcelona, Spain
    • Law, Matthew. Australian HIV Observational Database, The Kirby Institute, University of New South Wales Darlinghurst, Australia
    • Bendall, Courtney. Australian HIV Observational Database, The Kirby Institute, University of New South Wales Darlinghurst, Australia
    • Petoumenos, Kathy. Australian HIV Observational Database, The Kirby Institute, University of New South Wales Darlinghurst, Australia
    • Rockstroh, Jürgen. University Hospital Bonn, Germany
    • Wasmuth, Jan-Christian. University Hospital Bonn, Germany
    • Kabamba, Kabeya. Saint-Pierre University Hospital, Brussels, Belgium
    • Delforge, Marc. Saint-Pierre University Hospital, Brussels, Belgium
    • De Wit, Stephane. Saint-Pierre University Hospital, Brussels, Belgium
    • Berger, Florian. Center HIV Hepatogastroenterology Düsseldorf, Germany
    • Mauss, Stefan. Center HIV Hepatogastroenterology Düsseldorf, Germany
    • de Paz Sierra, Mariana. Cohorte LATINA (Argentinian component), Buenos Aires, Argentina
    • Losso, Marcelo. Cohorte LATINA (Argentinian component), Buenos Aires, Argentina
    • Belloso, Waldo H.. Cohorte LATINA (Argentinian component), Buenos Aires, Argentina
    • Leyes, Maria. University Hospital Son Espases, Palma de Mallorca, Spain
    • Campins, Antoni. University Hospital Son Espases, Palma de Mallorca, Spain
    • Mondi, Annalisa. Università Cattolica del Sacro Cuore Cohort, Rome, Italy
    • De Luca, Andrea. Università Cattolica del Sacro Cuore Cohort, Rome, Italy
    • Bernardino, Ignacio. University Hospital La Paz and IdiPAZ Biobanco, Madrid, Spain
    • Barriuso-Iglesias, Mónica. University Hospital La Paz and IdiPAZ Biobanco, Madrid, Spain
    • Torrecilla-Rodriguez, Ana. University Hospital La Paz and IdiPAZ Biobanco, Madrid, Spain
    • Gonzalez-Garcia, Juan. University Hospital La Paz and IdiPAZ Biobanco, Madrid, Spain
    • Arribas, José R.. University Hospital La Paz and IdiPAZ Biobanco, Madrid, Spain
    • Fanti, Iuri. Italian Cohort Naive for Antiretrovirals Foundation, Italy
    • Gel, Silvia. University Hospital Germans Trias i Pujol, Badalona
    • Puig, Jordi. University Hospital Germans Trias i Pujol, Badalona
    • Negredo, Eugenia. University Hospital Germans Trias i Pujol, Badalona
    • Gutierrez, Mar. University Hospital de la Santa Creu i Sant Pau Cohort, Autonomous University, Barcelona, Spain
    • Domingo, Pere. University Hospital de la Santa Creu i Sant Pau Cohort, Autonomous University, Barcelona, Spain
    • Fischer, Julia. University Hospital Cologne, Germany
    • Fätkenheuer, Gerd. University Hospital Cologne, Germany
    • Alonso-Villaverde, Carlos. Hospital Santa Tecla i Sant Pau, Tarragona, Spain
    • Macken, Alan. School of Medicine and Medical Science, University College Dublin
    • Woo, James. St James's Hospital
    • McGinty, Tara. Mater Misericordiae University Hospital, Dublin, Ireland
    • Mallon, Patrick. School of Medicine and Medical Science, University College Dublin
    • Mangili, Alexandra. Tufts University School of Medicine, Boston, Massachusetts
    • Skinner, Sally. Tufts University School of Medicine, Boston, Massachusetts
    • Wanke, Christine A.. Tufts University School of Medicine, Boston, Massachusetts
    • Reiss, Peter. AIDS Therapy Evaluation in the Netherlands, Amsterdam
    • Weber, Rainer. Swiss HIV Cohort Study
    • Bucher, Heiner C.. Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel
    • Fellay, Jacques. Institute of Microbiology, University Hospital Center, University of Lausanne
    • Telenti, Amalio. Institute of Microbiology, University Hospital Center, University of Lausanne
    • Tarr, Philip E.. Swiss HIV Cohort Study
    Document Type
    • Postprint
    Language
    • English
    Published in
    • Clinical Infectious Diseases, 2013, vol. 57, no. 1, p. 112-121. Oxford University Press
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:303450
    Summary
    We show in human immunodeficiency virus-positive persons that the coronary artery disease effect of an unfavorable genetic background is comparable to previous studies in the general population, and comparable in size to traditional risk factors and antiretroviral regimens known to increase cardiovascular risk