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Acute Cytomegalovirus Colitis Presenting during Primary HIV Infection: an Unusual Case of an Immune Reconstitution Inflammatory Syndrom

von Both, Ulrich ; Laffer, Reto ; Grube, Christina ; Bossart, Walter ; Gaspert, Ariana ; Gü nthard, Huldrych F.

In: Clinical Infectious Diseases, 2008, vol. 46, no. 4, p. e38-e40

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    Titre
    • Acute Cytomegalovirus Colitis Presenting during Primary HIV Infection: an Unusual Case of an Immune Reconstitution Inflammatory Syndrom
    Auteur
    • von Both, Ulrich. Division of Infectious Diseases and Hospital Epidemiology, Zurich, Switzerland
    • Laffer, Reto. Division of Infectious Diseases and Hospital Epidemiology, Zurich, Switzerland
    • Grube, Christina. Division of Infectious Diseases and Hospital Epidemiology, Zurich, Switzerland
    • Bossart, Walter. Institute of Medical Virology, Zurich, Switzerland
    • Gaspert, Ariana. Department of Pathology,University Hospital Zurich, Zurich, Switzerland
    • Gü nthard, Huldrych F.. Division of Infectious Diseases and Hospital Epidemiology, Zurich, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Clinical Infectious Diseases, 2008, vol. 46, no. 4, p. e38-e40. The University of Chicago Press
    Autre version électronique
    Classification
    • Santé
    Identifiant OAI-PMH
    • oai:doc.rero.ch:302717
    Summary
    Severe ulcerous cytomegalovirus pancolitis developed during primary human immunodeficiency virus (HIV) infection in a patient who underwent early combination antiretroviral treatment. This massive inflammatory process led to acute colon perforation. Serological testing demonstrated cytomegalovirus reactivation. Severe immunosuppression caused by primary HIV infection resulted in cytomegalovirus colitis, and initiation of early combination antiretroviral therapy triggered an immune reconstitution inflammatory syndrome potentially leading to colonic perforation