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The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected Individuals
Perkins, Molly R. ; Bartha, Istvan ; Timmer, J. Katherina ; Liebner, Julia C. ; Wollinsky, David ; Günthard, Huldrych F. ; Hauser, Christoph ; Bernasconi, Enos ; Hoffmann, Matthias ; Calmy, Alexandra ; Battegay, Manuel ; Telenti, Amalio ; Douek, Daniel C. ; Fellay, Jacques ; Aubert, V. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Bucher, H.C. ; Burton-Jeangros, C. ; Calmy, A. ; Cavassini, M. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, C.A. ; Gorgievski, M. ; Günthard, H. ; Haerry, D. ; Hasse, B. ; Hirsch, H.H. ; Hoffmann, M. ; Hösli, I. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Metzner, K. ; Müller, N. ; Nadal, D. ; Nicca, D. ; Pantaleo, G. ; Rauch, A. ; Regenass, S. ; Rickenbach, M. ; Rudin, C. ; Schöni-Affolter, F. ; Schmid, P. ; Schüpbach, J. ; Speck, R. ; Tarr, P. ; Telenti, A. ; Trkola, A. ; Vernazza, P. ; Weber, R. ; Yerly, S. ; Aubert, V. ; Battegay, M. ; Bernasconi, E. ; Böni, J. ; Bucher, H.C. ; Burton-Jeangros, C. ; Calmy, A. ; Cavassini, M. ; Dollenmaier, G. ; Egger, M. ; Elzi, L. ; Fehr, J. ; Fellay, J. ; Furrer, H. ; Fux, C.A. ; Gorgievski, M. ; Günthard, H. ; Haerry, D. ; Hasse, B. ; Hirsch, H.H. ; Hoffmann, M. ; Hösli, I. ; Kahlert, C. ; Kaiser, L. ; Keiser, O. ; Klimkait, T. ; Kouyos, R. ; Kovari, H. ; Ledergerber, B. ; Martinetti, G. ; Martinez de Tejada, B. ; Metzner, K. ; Müller, N. ; Nadal, D. ; Nicca, D. ; Pantaleo, G. ; Rauch, A. ; Regenass, S. ; Rickenbach, M. ; Rudin, C. ; Schöni-Affolter, F. ; Schmid, P. ; Schüpbach, J. ; Speck, R. ; Tarr, P. ; Telenti, A. ; Trkola, A. ; Vernazza, P. ; Weber, R. ; Yerly, S.
In: The Journal of Infectious Diseases, 2015, vol. 212, no. 4, p. 578-584
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- Titre
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- The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected Individuals
- Auteur
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- Perkins, Molly R.. Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland
- Bartha, Istvan. Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne
- Timmer, J. Katherina. Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland
- Liebner, Julia C.. Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland
- Wollinsky, David. Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland
- Günthard, Huldrych F.. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich and University of Zurich
- Hauser, Christoph. University Clinic of Infectious Diseases, University Hospital Bern and University of Bern
- Bernasconi, Enos. Division of Infectious Diseases, Regional Hospital Lugano
- Hoffmann, Matthias. Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St Gallen
- Calmy, Alexandra. HIV Unit, Department of Internal Medicine, Geneva University Hospital
- Battegay, Manuel. Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, University Hospital Basel, University of Basel, Switzerland
- Telenti, Amalio. Institute of Microbiology, University Hospital and University of Lausanne
- Douek, Daniel C.. Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland
- Fellay, Jacques. Global Health Institute, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne
- Aubert, V.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Battegay, M.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Bernasconi, E.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Böni, J.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Bucher, H.C.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Burton-Jeangros, C.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Calmy, A.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Cavassini, M.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Dollenmaier, G.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Egger, M.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Elzi, L.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Fehr, J.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Fellay, J.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Furrer, H.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Fux, C.A.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Gorgievski, M.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Günthard, H.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Haerry, D.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Hasse, B.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Hirsch, H.H.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Hoffmann, M.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Hösli, I.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Kahlert, C.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Kaiser, L.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Keiser, O.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Klimkait, T.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Kouyos, R.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Kovari, H.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Ledergerber, B.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Martinetti, G.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Martinez de Tejada, B.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Metzner, K.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Müller, N.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Nadal, D.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Nicca, D.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Pantaleo, G.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Rauch, A.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Regenass, S.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Rickenbach, M.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Rudin, C.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Schöni-Affolter, F.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Schmid, P.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Schüpbach, J.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Speck, R.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Tarr, P.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Telenti, A.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Trkola, A.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Vernazza, P.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Weber, R.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Yerly, S.. National Institute of Allergy and Infectious Disease, National Institutes of Health, Human Immunology Section, Vaccine Research Center, Bethesda, Maryland, Global Health Institute, Lausanne, Institute of Microbiology, Division of Infectious Diseases and Hospital Epidemiology, University Clinic of Infectious Diseases, Division of Infectious Diseases, Division of Infectious Diseases and Hospital Epidemiology, HIV Unit, Department of Internal Medicine, Division of Infectious Diseases and Hospital Epidemiology, Departments of Clinical and Biomedical Research, Switzerland
- Aubert, V.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Battegay, M.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Bernasconi, E.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Böni, J.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Bucher, H.C.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Burton-Jeangros, C.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Calmy, A.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Cavassini, M.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Dollenmaier, G.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Egger, M.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Elzi, L.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Fehr, J.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Fellay, J.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Furrer, H.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Fux, C.A.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Gorgievski, M.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Günthard, H.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Haerry, D.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Hasse, B.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Hirsch, H.H.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Hoffmann, M.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Hösli, I.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Kahlert, C.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Kaiser, L.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Keiser, O.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Klimkait, T.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Kouyos, R.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Kovari, H.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Ledergerber, B.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Martinetti, G.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Martinez de Tejada, B.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Metzner, K.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Müller, N.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Nadal, D.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Nicca, D.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Pantaleo, G.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Rauch, A.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Regenass, S.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Rickenbach, M.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Rudin, C.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Schöni-Affolter, F.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Schmid, P.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Schüpbach, J.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Speck, R.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Tarr, P.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Telenti, A.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Trkola, A.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Vernazza, P.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Weber, R.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Yerly, S.. Correspondence: Jacques Fellay, MD, PhD, EPFL School of Life Sciences, Station 19, 1015 Lausanne, Switzerland (
- Type de document
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- Postprint
- Langue
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- Anglais
- Publié dans
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- The Journal of Infectious Diseases, 2015, vol. 212, no. 4, p. 578-584. Oxford University Press
- Autre version électronique
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- Publisher's version : https://doi.org/10.1093/infdis/jiv089
- Classification
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- Santé
- Mots clés
- Identifiant OAI-PMH
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- oai:doc.rero.ch:300725
- Summary
- Systemic immune activation, a major determinant of human immunodeficiency virus (HIV) disease progression, is the result of a complex interplay between viral replication, dysregulation of the immune system, and microbial translocation due to gut mucosal damage. Although human genetic variants influencing HIV load have been identified, it is unknown how much the host genetic background contributes to interindividual differences in other determinants of HIV pathogenesis such as gut damage and microbial translocation. Using samples and data from 717 untreated participants in the Swiss HIV Cohort Study and a genome-wide association study design, we searched for human genetic determinants of plasma levels of intestinal fatty acid-binding protein (I-FABP/FABP2), a marker of gut damage, and of soluble CD14 (sCD14), a marker of lipopolysaccharide bioactivity and microbial translocation. We also assessed the correlations between HIV load, sCD14, and I-FABP. Although we found no genome-wide significant determinant of the tested plasma markers, we observed strong associations between sCD14 and both HIV load and I-FABP, shedding new light on the relationships between processes that drive progression of untreated HIV infection