Serotonin Syndrome after Concomitant Treatment with Linezolid and Citalopram

Bernard, L. ; Stern, R. ; Lew, D. ; Hoffmeyer, P.

In: Clinical Infectious Diseases, 2003, vol. 36, no. 9, p. -

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    Summary
    Linezolid, a new synthetic antimicrobial, is an important weapon against methicillin-resistant Staphylococcus aureus (MRSA). Although there are reports of serotonin syndrome developing after concomitant use of linezolid and the selective serotonin reuptake inhibitor paroxitene, this report concerns a patient receiving citalopram who developed thrombocytopenia, serotonin syndrome, and lactic acidosis and died following long-term linezolid therapy