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Circadian elevation of IL-6 levels in Muckle-Wells syndrome: a disorder of the neuro-immune axis?

Gerbig, A W. ; Dahinden, C A. ; Mullis, P. ; Hunziker, T.

In: QJM : monthly journal of the Association of Physicians, 1998, vol. 91, no. 7, p. 489-492

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    Titre
    • Circadian elevation of IL-6 levels in Muckle-Wells syndrome: a disorder of the neuro-immune axis?
    Auteur
    • Gerbig, A W.. Department of Dermatology, University of Bern, Switzerland.
    • Dahinden, C A.. Department of Dermatology, University of Bern, Switzerland.
    • Mullis, P.. Department of Dermatology, University of Bern, Switzerland.
    • Hunziker, T.. Department of Dermatology, University of Bern, Switzerland.
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • QJM : monthly journal of the Association of Physicians, 1998, vol. 91, no. 7, p. 489-492
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:293927
    Summary
    Muckle-Wells syndrome (MWS) is a rare autosomal dominant hereditary disorder characterized by chronic recurrent urticaria, arthralgia, sensorineural deafness, and in some cases nephropathy due to amyloidosis (AA type). We report a 21-year-old woman and her father, both suffering from this syndrome, in whom elevated serum levels of IL-6 could be documented during the flares of urticaria, and discuss the relevance of this finding for MWS