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Validation of the Consensus-Definition for Cancer Cachexia and evaluation of a classification model—a study based on data from an international multicentre project (EPCRC-CSA)

Blum, D. ; Stene, G. B. ; Solheim, T. S. ; Fayers, P. ; Hjermstad, M. J. ; Baracos, V. E. ; Fearon, K. ; Strasser, F. ; Kaasa, S. ; Block Lieve, Van den ; Koen, Meeussen ; Sarah, Brearley ; Augusto, Caraceni ; Joachim, Cohen ; Massimo, Costantini ; Anneke, Francke ; Richard, Harding ; Higginson Irene, J. ; Stein, Kaasa ; Karen, Linden ; Guido, Miccinesi ; Bregje, Onwuteaka-Philipsen ; Koen, Pardon ; Roeline, Pasman ; Sophie, Pautex ; Sheila, Payne ; Luc, Deliens

In: Annals of Oncology, 2014, vol. 25, no. 8, p. 1635-1642

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    Titre
    • Validation of the Consensus-Definition for Cancer Cachexia and evaluation of a classification model—a study based on data from an international multicentre project (EPCRC-CSA)
    Auteur
    • Blum, D.. European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim
    • Stene, G. B.. European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim
    • Solheim, T. S.. European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim
    • Fayers, P.. European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim
    • Hjermstad, M. J.. European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim
    • Baracos, V. E.. Department of Oncology, Division of Palliative Care Medicine, University of Alberta, Alberta, Canada
    • Fearon, K.. Clinical and Surgical Sciences (Surgery), University of Edinburgh, Royal Infirmary, Edinburgh, UK
    • Strasser, F.. European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim
    • Kaasa, S.. European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim
    • Block Lieve, Van den. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Koen, Meeussen. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Sarah, Brearley. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Augusto, Caraceni. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Joachim, Cohen. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Massimo, Costantini. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Anneke, Francke. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Richard, Harding. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Higginson Irene, J.. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Stein, Kaasa. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Karen, Linden. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Guido, Miccinesi. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Bregje, Onwuteaka-Philipsen. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Koen, Pardon. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Roeline, Pasman. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Sophie, Pautex. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Sheila, Payne. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    • Luc, Deliens. Faculty of Medicine, Norwegian University of Science and Technology (NTNU), European Palliative Care Research Centre, Trondheim, Cancer Clinic, St Olavs Hospital, Trondheim, Department of Neuroscience, Faculty of Medicine, Trondheim, Aberdeen, Department of Oncology, Regional Centre for Excellence in Palliative Care, Ullevål, Oslo, Department of Oncology, Division of Palliative Care Medicine, Alberta, Clinical and Surgical Sciences (Surgery), Edinburgh, Department of Internal Medicine and Palliative Center Cantonal Hospital, St Gallen, Norway, UK, Norway, Canada, UK, Switzerland
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Annals of Oncology, 2014, vol. 25, no. 8, p. 1635-1642. Oxford University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:293218
    Summary
    A cancer cachexia classification into stages is warranted in order to guide treatment decisions and clinical trial inclusion. Weight loss and BMI clearly discriminate between non-cachectic and cachectic patients both with regards to all the domains (Intake, Catabolism and Function) and survival. The precachexia stage might be better defined by additional factors in order to be discriminative