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Toward community standards in the quest for orthologs

Dessimoz, Christophe ; Gabaldón, Toni ; Roos, David S. ; Sonnhammer, Erik L. L. ; Herrero, Javier ; Altenhoff, Adrian ; Apweiler, Rolf ; Ashburner, Michael ; Blake, Judith ; Boeckmann, Brigitte ; Bridge, Alan ; Bruford, Elspeth ; Cherry, Mike ; Conte, Matthieu ; Dannie, Durand ; Datta, Ruchira ; Dessimoz, Christophe ; Domelevo Entfellner, Jean-Baka ; Ebersberger, Ingo ; Gabaldón, Toni ; Galperin, Michael ; Herrero, Javier ; Joseph, Jacob ; Koestler, Tina ; Kriventseva, Evgenia ; Lecompte, Odile ; Leunissen, Jack ; Lewis, Suzanna ; Linard, Benjamin ; Livstone, Michael S. ; Lu, Hui-Chun ; Martin, Maria ; Mazumder, Raja ; Messina, David ; Miele, Vincent ; Muffato, Matthieu ; Perrière, Guy ; Punta, Marco ; Roos, David ; Rouard, Mathieu ; Schmitt, Thomas ; Schreiber, Fabian ; Silva, Alan ; Sjölander, Kimmen ; Škunca, Nives ; Sonnhammer, Erik ; Stanley, Eleanor ; Szklarczyk, Radek ; Thomas, Paul ; Uchiyama, Ikuo ; Van Bel, Michiel ; Vandepoele, Klaas ; Vilella, Albert J. ; Yates, Andrew ; Zdobnov, Evgeny ; Dessimoz, Christophe ; Gabaldón, Toni ; Roos, David S. ; Sonnhammer, Erik L. L. ; Herrero, Javier ; Altenhoff, Adrian ; Apweiler, Rolf ; Ashburner, Michael ; Blake, Judith ; Boeckmann, Brigitte ; Bridge, Alan ; Bruford, Elspeth ; Cherry, Mike ; Conte, Matthieu ; Dannie, Durand ; Datta, Ruchira ; Dessimoz, Christophe ; Domelevo Entfellner, Jean-Baka ; Ebersberger, Ingo ; Gabaldón, Toni ; Galperin, Michael ; Herrero, Javier ; Joseph, Jacob ; Koestler, Tina ; Kriventseva, Evgenia ; Lecompte, Odile ; Leunissen, Jack ; Lewis, Suzanna ; Linard, Benjamin ; Livstone, Michael S. ; Lu, Hui-Chun ; Martin, Maria ; Mazumder, Raja ; Messina, David ; Miele, Vincent ; Muffato, Matthieu ; Perrière, Guy ; Punta, Marco ; Roos, David ; Rouard, Mathieu ; Schmitt, Thomas ; Schreiber, Fabian ; Silva, Alan ; Sjölander, Kimmen ; Škunca, Nives ; Sonnhammer, Erik ; Stanley, Eleanor ; Szklarczyk, Radek ; Thomas, Paul ; Uchiyama, Ikuo ; Van Bel, Michiel ; Vandepoele, Klaas ; Vilella, Albert J. ; Yates, Andrew ; Zdobnov, Evgeny

In: Bioinformatics, 2012, vol. 28, no. 6, p. 900-904

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    Titre
    • Toward community standards in the quest for orthologs
    Auteur
    • Dessimoz, Christophe. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Gabaldón, Toni. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Roos, David S.. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Sonnhammer, Erik L. L.. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Herrero, Javier. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Altenhoff, Adrian
    • Apweiler, Rolf
    • Ashburner, Michael
    • Blake, Judith
    • Boeckmann, Brigitte
    • Bridge, Alan
    • Bruford, Elspeth
    • Cherry, Mike
    • Conte, Matthieu
    • Dannie, Durand
    • Datta, Ruchira
    • Dessimoz, Christophe
    • Domelevo Entfellner, Jean-Baka
    • Ebersberger, Ingo
    • Gabaldón, Toni
    • Galperin, Michael
    • Herrero, Javier
    • Joseph, Jacob
    • Koestler, Tina
    • Kriventseva, Evgenia
    • Lecompte, Odile
    • Leunissen, Jack
    • Lewis, Suzanna
    • Linard, Benjamin
    • Livstone, Michael S.
    • Lu, Hui-Chun
    • Martin, Maria
    • Mazumder, Raja
    • Messina, David
    • Miele, Vincent
    • Muffato, Matthieu
    • Perrière, Guy
    • Punta, Marco
    • Roos, David
    • Rouard, Mathieu
    • Schmitt, Thomas
    • Schreiber, Fabian
    • Silva, Alan
    • Sjölander, Kimmen
    • Škunca, Nives
    • Sonnhammer, Erik
    • Stanley, Eleanor
    • Szklarczyk, Radek
    • Thomas, Paul
    • Uchiyama, Ikuo
    • Van Bel, Michiel
    • Vandepoele, Klaas
    • Vilella, Albert J.
    • Yates, Andrew
    • Zdobnov, Evgeny
    • Dessimoz, Christophe. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Gabaldón, Toni. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Roos, David S.. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Sonnhammer, Erik L. L.. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Herrero, Javier. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Altenhoff, Adrian. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Apweiler, Rolf. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Ashburner, Michael. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Blake, Judith. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Boeckmann, Brigitte. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Bridge, Alan. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Bruford, Elspeth. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Cherry, Mike. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Conte, Matthieu. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Dannie, Durand. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Datta, Ruchira. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Dessimoz, Christophe. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Domelevo Entfellner, Jean-Baka. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Ebersberger, Ingo. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Gabaldón, Toni. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Galperin, Michael. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Herrero, Javier. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Joseph, Jacob. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Koestler, Tina. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Kriventseva, Evgenia. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Lecompte, Odile. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Leunissen, Jack. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Lewis, Suzanna. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Linard, Benjamin. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Livstone, Michael S.. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Lu, Hui-Chun. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Martin, Maria. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Mazumder, Raja. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Messina, David. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Miele, Vincent. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Muffato, Matthieu. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Perrière, Guy. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Punta, Marco. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Roos, David. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Rouard, Mathieu. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Schmitt, Thomas. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Schreiber, Fabian. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Silva, Alan. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Sjölander, Kimmen. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Škunca, Nives. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Sonnhammer, Erik. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Stanley, Eleanor. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Szklarczyk, Radek. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Thomas, Paul. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Uchiyama, Ikuo. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Van Bel, Michiel. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Vandepoele, Klaas. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Vilella, Albert J.. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Yates, Andrew. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    • Zdobnov, Evgeny. ETH Zurich and Swiss Institute of Bioinformatics, Universitätstrasse 6, 8092 Zürich, Switzerland, 2Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), and UPF. Dr. Aiguader, 88, 08003 Barcelona, Spain, 3Department of Biology and Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, PA 19104, USA, 4Stockholm Bioinformatics Center, Swedish eScience Research Center, Department of Biochemistry and Biophysics, Stockholm University, Science for Life Laboratory, Box 1031, SE-17121 Solna, Sweden, 5European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Type de document
    • Postprint
    Identifiant OAI-PMH
    • oai:doc.rero.ch:292993
    Summary
    The identification of orthologs—genes pairs descended from a common ancestor through speciation, rather than duplication—has emerged as an essential component of many bioinformatics applications, ranging from the annotation of new genomes to experimental target prioritization. Yet, the development and application of orthology inference methods is hampered by the lack of consensus on source proteomes, file formats and benchmarks. The second ‘Quest for Orthologs' meeting brought together stakeholders from various communities to address these challenges. We report on achievements and outcomes of this meeting, focusing on topics of particular relevance to the research community at large. The Quest for Orthologs consortium is an open community that welcomes contributions from all researchers interested in orthology research and applications. Contact: dessimoz@ebi.ac.uk