Fulltext

Oral abstracts 1: SpondyloarthropathiesO1. Detecting axial spondyloarthritis amongst primary care back pain referrals

Harris, Claire ; Remedios, Denis ; Aptowitzer, Tanya ; Keat, Andrew ; Hamilton, Louise ; Guile, Geoffrey ; Belkhiri, Abdelghani ; Newman, David ; Toms, Andoni ; Macgregor, Alex ; Gaffney, Karl ; Morton, Linda ; Jones, Gareth T. ; MacDonald, Alan G. ; Downham, Christina ; Macfarlane, Gary J. ; Tillett, William ; Jadon, Deepak ; Wallis, Dinny ; Costa, Luisa ; Waldron, Nicola ; Griffith, Nina ; Cavill, Charlotte ; Korendowych, Eleanor ; de Vries, Corinne ; McHugh, Neil ; Iaremenko, Oleg ; Fedkov, Dmytro ; Emery, Paul ; Baeten, Dominique ; Sieper, Joachim ; Braun, Jurgen ; van der Heijde, D. ; McInnes, Iain ; Van Laar, Jaap ; Landewe, R. ; Wordsworth, Bryan P. ; Wollenhaupt, Jurgen ; Kellner, Herbert ; Paramarta, I. ; Bertolino, Arthur ; Wright, Andrew M. ; Hueber, Wolfgang ; Sofat, Nidhi ; Smee, Cori ; Hermansson, Monika ; Wajed, Julekha ; Sanyal, Kaushik ; Kiely, Patrick ; Howard, Matthew ; Howe, Franklyn A. ; Barrick, Thomas R. ; Abraham, Ajay M. ; Pearce, Mark S. ; Mann, Kay D. ; Francis, Roger M. ; Birrell, Fraser ; Carr, Andrew ; Macleod, Iain ; Ng, Wan-Fai ; Kavanaugh, Arthur ; van der Heijde, Desiree ; Chattopadhyay, Chandrabhusan ; Gladman, Dafna ; Mease, Philip ; McInnes, Iain ; Krueger, Gerald ; Xu, Weichun ; Goldstein, Neil ; Beutler, Anna ; Van Laar, Jaap ; Baraliakos, Xenofon ; Braun, Jurgen ; Laurent, Didier D. ; Baeten, Dominique ; van der Heijde, D. ; Sieper, Joachim ; Emery, Paul ; McInnes, Iain ; Landewe, R. ; Wordsworth, Bryan P. ; Wollenhaupt, Jürgen ; Kellner, Herbert ; Wright, Andrew M. ; Gsteiger, Sandro ; Hueber, Wolfgang ; Conaghan, Philip G. ; Peterfy, Charles G. ; DiCarlo, Julie ; Olech, Ewa ; Alberts, Alan R. ; Alper, Jeffrey A. ; Devenport, Jenny ; Anisfeld, Andrew M. ; Troum, Orrin M. ; Cooper, Philip ; Gimpel, Mo ; Deakin, Greg ; Jameson, Karen ; Godtschailk, Malcolm ; Gadola, Stephan ; Stokes, Maria ; Cooper, Cyrus ; Gordon, Caroline ; Kalunian, K. ; Petri, M. ; Strand, V. ; Kilgallen, B. ; Barry, A. ; Wallace, D. ; Flurey, Caroline A. ; Morris, Marianne ; Pollock, Jon ; Hughes, Rod ; Richards, Pam ; Hewlett, Sarah

In: Rheumatology, 2012, vol. 51, p. iii19-iii26

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    Titre
    • Oral abstracts 1: SpondyloarthropathiesO1. Detecting axial spondyloarthritis amongst primary care back pain referrals
    Auteur
    • Harris, Claire. Rheumatology Department, Northwick Park Hospital, Harrow, United Kingdom; Radiology Department, Northwick Park Hospital, Harrow, United Kingdom; Physiotherapy Department, Northwick Park Hospital, Harrow, United Kingdom
    • Remedios, Denis. Rheumatology Department, Northwick Park Hospital, Harrow, United Kingdom; Radiology Department, Northwick Park Hospital, Harrow, United Kingdom; Physiotherapy Department, Northwick Park Hospital, Harrow, United Kingdom
    • Aptowitzer, Tanya. Rheumatology Department, Northwick Park Hospital, Harrow, United Kingdom; Radiology Department, Northwick Park Hospital, Harrow, United Kingdom; Physiotherapy Department, Northwick Park Hospital, Harrow, United Kingdom
    • Keat, Andrew. Rheumatology Department, Northwick Park Hospital, Harrow, United Kingdom; Radiology Department, Northwick Park Hospital, Harrow, United Kingdom; Physiotherapy Department, Northwick Park Hospital, Harrow, United Kingdom
    • Hamilton, Louise. Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Radiology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Norwich Medical School, University of East Anglia, Norwich, United Kingdom
    • Guile, Geoffrey. Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Radiology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Norwich Medical School, University of East Anglia, Norwich, United Kingdom
    • Belkhiri, Abdelghani. Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Radiology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Norwich Medical School, University of East Anglia, Norwich, United Kingdom
    • Newman, David. Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Radiology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Norwich Medical School, University of East Anglia, Norwich, United Kingdom
    • Toms, Andoni. Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Radiology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Norwich Medical School, University of East Anglia, Norwich, United Kingdom
    • Macgregor, Alex. Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Radiology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Norwich Medical School, University of East Anglia, Norwich, United Kingdom
    • Gaffney, Karl. Rheumatology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Radiology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom; Norwich Medical School, University of East Anglia, Norwich, United Kingdom
    • Morton, Linda. Aberdeen Musculoskeletal Research Group (Epidemiology), University of Aberdeen, Aberdeen, United Kingdom; Department of Rheumatology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • Jones, Gareth T.. Aberdeen Musculoskeletal Research Group (Epidemiology), University of Aberdeen, Aberdeen, United Kingdom; Department of Rheumatology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • MacDonald, Alan G.. Aberdeen Musculoskeletal Research Group (Epidemiology), University of Aberdeen, Aberdeen, United Kingdom; Department of Rheumatology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • Downham, Christina. Aberdeen Musculoskeletal Research Group (Epidemiology), University of Aberdeen, Aberdeen, United Kingdom; Department of Rheumatology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • Macfarlane, Gary J.. Aberdeen Musculoskeletal Research Group (Epidemiology), University of Aberdeen, Aberdeen, United Kingdom; Department of Rheumatology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    • Tillett, William. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • Jadon, Deepak. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • Wallis, Dinny. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • Costa, Luisa. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • Waldron, Nicola. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • Griffith, Nina. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • Cavill, Charlotte. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • Korendowych, Eleanor. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • de Vries, Corinne. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • McHugh, Neil. Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom; Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom
    • Iaremenko, Oleg. Department of Internal Medicine, National Medical University O.O.Bogomolets, Kyiv, Ukraine
    • Fedkov, Dmytro. Department of Internal Medicine, National Medical University O.O.Bogomolets, Kyiv, Ukraine
    • Emery, Paul. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Baeten, Dominique. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Sieper, Joachim. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Braun, Jurgen. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • van der Heijde, D.. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • McInnes, Iain. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Van Laar, Jaap. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Landewe, R.. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Wordsworth, Bryan P.. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Wollenhaupt, Jurgen. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Kellner, Herbert. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Paramarta, I.. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Bertolino, Arthur. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Wright, Andrew M.. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Hueber, Wolfgang. Department of Medicine, University of Leeds, Leeds, United Kingdom; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Gastroenterology, Charite Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; TM Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Sofat, Nidhi. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Smee, Cori. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Hermansson, Monika. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Wajed, Julekha. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Sanyal, Kaushik. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Kiely, Patrick. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Howard, Matthew. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Howe, Franklyn A.. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Barrick, Thomas R.. Rheumatology, St George's, University of London, London, United Kingdom; Biomedical Sciences, St George's, University of London, London, United Kingdom; Institute of Psychiatry, King's College London, London, United Kingdom; Clinical Sciences, St George's, University of London, London, United Kingdom
    • Abraham, Ajay M.. Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Pearce, Mark S.. Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Mann, Kay D.. Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Francis, Roger M.. Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Birrell, Fraser. Institute of Health and Society, Newcastle University, Newcastle upon Tyne, United Kingdom; Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Carr, Andrew. Dental and Maxillofacial Radiology, Newcastle Dental Hospital, Newcastle upon Tyne, United Kingdom; Musculoskeletal Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Macleod, Iain. Dental and Maxillofacial Radiology, Newcastle Dental Hospital, Newcastle upon Tyne, United Kingdom; Musculoskeletal Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Ng, Wan-Fai. Dental and Maxillofacial Radiology, Newcastle Dental Hospital, Newcastle upon Tyne, United Kingdom; Musculoskeletal Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom
    • Kavanaugh, Arthur. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • van der Heijde, Desiree. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • Chattopadhyay, Chandrabhusan. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • Gladman, Dafna. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • Mease, Philip. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • McInnes, Iain. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • Krueger, Gerald. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • Xu, Weichun. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • Goldstein, Neil. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • Beutler, Anna. Immunology, University of California, San Diego, San Diego, California, United States of America; Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Rheumatology, Wrightington Hospital, Wigan, United Kingdom; Rheumatology, Toronto Western Hospital, Toronto, Ontario, Canada; Rheumatology, Swedish Medical Center/ University of Washington, Seattle, Washington, United States of America; Rheumatology, University of Glasgow, Glasgow, United Kingdom; Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, United States of America; Immunology, Janssen Research and Development, Inc., Malvern, Pennsylvania,United States of America
    • Van Laar, Jaap. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Baraliakos, Xenofon. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Braun, Jurgen. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Laurent, Didier D.. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Baeten, Dominique. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • van der Heijde, D.. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Sieper, Joachim. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Emery, Paul. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • McInnes, Iain. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Landewe, R.. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Wordsworth, Bryan P.. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Wollenhaupt, Jürgen. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Kellner, Herbert. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Wright, Andrew M.. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Gsteiger, Sandro. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Hueber, Wolfgang. Department of Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Medicine, Rheumazentrum Ruhrgebiet, Herne, Germany; Translational Medicine Dermatology, Novartis Institutes for BioMedical Research, Basel, Switzerland; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; Department of Gastroenterology, Charitè Campus Benjamin Franklin, Berlin, Germany; Department of Medicine, University of Leeds, Leeds, United Kingdom; Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom; Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands; Department of Medicine, Nuffield Orthopaedic Centre, Oxford, United Kingdom; Klinik für Rheumatologie, Eilbeck Hospital, Hamburg, Germany; Department of Medicine, Center for Inflammatory Joint Diseases, Munich, Germany; M&S Statistics, Novartis Pharma AG, Basel, Switzerland
    • Conaghan, Philip G.. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • Peterfy, Charles G.. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • DiCarlo, Julie. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • Olech, Ewa. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • Alberts, Alan R.. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • Alper, Jeffrey A.. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • Devenport, Jenny. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • Anisfeld, Andrew M.. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • Troum, Orrin M.. NIHR-Leeds Biomedical Research Unit and Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom, Spire Sciences LLC, San Francisco, CA, USA, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA, West Broward Rheumatology Associates, Inc., Tamarac, FL, USA, Jeffrey Alper MD Research, Naples, FL, USA, Genentech, South San Francisco, CA, USC Keck School of Medicine, Santa Monica, CA, USA
    • Cooper, Philip. University of Southampton, MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom; NIHR Musculoskeletal BRU, University of Southampton, Southampton, United Kingdom; Department of Sports Medicine, Southampton Football Club, Southampton, United Kingdom
    • Gimpel, Mo. University of Southampton, MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom; NIHR Musculoskeletal BRU, University of Southampton, Southampton, United Kingdom; Department of Sports Medicine, Southampton Football Club, Southampton, United Kingdom
    • Deakin, Greg. University of Southampton, MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom; NIHR Musculoskeletal BRU, University of Southampton, Southampton, United Kingdom; Department of Sports Medicine, Southampton Football Club, Southampton, United Kingdom
    • Jameson, Karen. University of Southampton, MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom; NIHR Musculoskeletal BRU, University of Southampton, Southampton, United Kingdom; Department of Sports Medicine, Southampton Football Club, Southampton, United Kingdom
    • Godtschailk, Malcolm. University of Southampton, MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom; NIHR Musculoskeletal BRU, University of Southampton, Southampton, United Kingdom; Department of Sports Medicine, Southampton Football Club, Southampton, United Kingdom
    • Gadola, Stephan. University of Southampton, MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom; NIHR Musculoskeletal BRU, University of Southampton, Southampton, United Kingdom; Department of Sports Medicine, Southampton Football Club, Southampton, United Kingdom
    • Stokes, Maria. University of Southampton, MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom; NIHR Musculoskeletal BRU, University of Southampton, Southampton, United Kingdom; Department of Sports Medicine, Southampton Football Club, Southampton, United Kingdom
    • Cooper, Cyrus. University of Southampton, MRC Lifecourse Epidemiology Unit, Southampton, United Kingdom; NIHR Musculoskeletal BRU, University of Southampton, Southampton, United Kingdom; Department of Sports Medicine, Southampton Football Club, Southampton, United Kingdom
    • Gordon, Caroline. Rheumatology, University of Birmingham, Birmingham, United Kingdom; University of California, San Diego, School of Medicine, La Jolla, California, United States of America; Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America; Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, United States of America; UCB Inc., Smyrna, Georgia, United States of America; Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, United States of America
    • Kalunian, K.. Rheumatology, University of Birmingham, Birmingham, United Kingdom; University of California, San Diego, School of Medicine, La Jolla, California, United States of America; Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America; Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, United States of America; UCB Inc., Smyrna, Georgia, United States of America; Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, United States of America
    • Petri, M.. Rheumatology, University of Birmingham, Birmingham, United Kingdom; University of California, San Diego, School of Medicine, La Jolla, California, United States of America; Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America; Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, United States of America; UCB Inc., Smyrna, Georgia, United States of America; Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, United States of America
    • Strand, V.. Rheumatology, University of Birmingham, Birmingham, United Kingdom; University of California, San Diego, School of Medicine, La Jolla, California, United States of America; Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America; Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, United States of America; UCB Inc., Smyrna, Georgia, United States of America; Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, United States of America
    • Kilgallen, B.. Rheumatology, University of Birmingham, Birmingham, United Kingdom; University of California, San Diego, School of Medicine, La Jolla, California, United States of America; Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America; Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, United States of America; UCB Inc., Smyrna, Georgia, United States of America; Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, United States of America
    • Barry, A.. Rheumatology, University of Birmingham, Birmingham, United Kingdom; University of California, San Diego, School of Medicine, La Jolla, California, United States of America; Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America; Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, United States of America; UCB Inc., Smyrna, Georgia, United States of America; Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, United States of America
    • Wallace, D.. Rheumatology, University of Birmingham, Birmingham, United Kingdom; University of California, San Diego, School of Medicine, La Jolla, California, United States of America; Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America; Division of Immunology and Rheumatology, Stanford University, Palo Alto, California, United States of America; UCB Inc., Smyrna, Georgia, United States of America; Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, California, United States of America
    • Flurey, Caroline A.. Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom; Rheumatology, University Hospitals Bristol, Bristol, United Kingdom; Rheumatology, St Peter's Hospital, Chertsey, United Kingdom
    • Morris, Marianne. Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom; Rheumatology, University Hospitals Bristol, Bristol, United Kingdom; Rheumatology, St Peter's Hospital, Chertsey, United Kingdom
    • Pollock, Jon. Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom; Rheumatology, University Hospitals Bristol, Bristol, United Kingdom; Rheumatology, St Peter's Hospital, Chertsey, United Kingdom
    • Hughes, Rod. Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom; Rheumatology, University Hospitals Bristol, Bristol, United Kingdom; Rheumatology, St Peter's Hospital, Chertsey, United Kingdom
    • Richards, Pam. Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom; Rheumatology, University Hospitals Bristol, Bristol, United Kingdom; Rheumatology, St Peter's Hospital, Chertsey, United Kingdom
    • Hewlett, Sarah. Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom; Rheumatology, University Hospitals Bristol, Bristol, United Kingdom; Rheumatology, St Peter's Hospital, Chertsey, United Kingdom
    Type de document
    • Postprint
    Identifiant OAI-PMH
    • oai:doc.rero.ch:290228
    Summary
    Background: Inflammatory back pain (IBP) is an early feature of ankylosing spondylitis (AS) and its detection offers the prospect of early diagnosis of AS. However, since back pain is very common but only a very small minority of back pain sufferers have ASpA or AS, screening of back pain sufferers for AS is problematic. In early disease radiographs are often normal so that fulfilment of diagnostic criteria for AS is impossible though a diagnosis of axial SpA can be made if MRI evidence of sacroiliitis is present. This pilot study was designed to indicate whether a cost-effective pick up rate for ASpA/early AS could be achieved by identifying adults with IBP stratified on the basis of age. Methods: Patients aged between 18 and 45 years who were referred to a hospital physiotherapy service with back pain of more than 3 months duration were assessed for IBP. All were asked to complete a questionnaire based on the Berlin IBP criteria. Those who fulfilled IBP criteria were also asked to complete a second short questionnaire enquiring about SpA comorbidities, to have a blood test for HLA-B27 and CRP level and to undergo an MRI scan of the sacroiliac joints. This was a limited scan, using STIR, diffusion-weighted, T1 and T2 sequences of the sacroiliac joints to minimize time in the scanner and cost. The study was funded by a research grant from Abbott Laboratories Ltd. Results: 50 sequential patients agreed to participate in the study and completed the IBP questionnaire. Of these 27 (54%) fulfilled criteria for IBP. Of these, 2 patients reported a history of an SpA comorbidity - 1 psoriasis; 1 ulcerative colitis - and 3 reported a family history of an SpA comorbidity - 2 psoriasis; 1 Crohn's disease. 4 were HLA-B27 positive, though results were not available for 7. Two patients had marginally raised CRP levels (6, 10 -NR ≤ 5). 19 agreed to undergo MRI scanning of the sacroiliac joints and lumbar spine; 4 scans were abnormal, showing evidence of bilateral sacroiliitis on STIR sequences. In all cases the changes met ASAS criteria but were limited. Of these 4 patients 3 were HLA-B27 positive but none gave a personal or family history of an SpA-associated comorbidity and all had normal CRP levels. Conclusions: This was a pilot study yielding only limited conclusions. However, it is clear that: Screening of patients referred for physiotherapy for IBP is straightforward, inexpensive and quick. It appears that IBP is more prevalent in young adults than overall population data suggest so that targeting this population may be efficient. IBP questionnaires could be administered routinely during a physiotherapy assessment. HLA-B27 testing in this group of patients with IBP is a suitable screening tool. The sacroiliac joint changes identified were mild and their prognostic significance is not yet clear so that the value of early screening needs further evaluation. Disclosure statement: C.H. received research funding for this study from Abbott. A.K. received research funding for this study, and speaker and consultancy fees, from Abbott. All other authors have declared no conflicts of interest