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Proteomic profiling of fibroblasts isolated from chronic wounds identifies disease-relevant signaling pathways

Berberich, Bettina ; Thriene, Kerstin ; Gretzmeier, Christine ; Kühl, Tobias ; Bayer, Hans ; Athanasiou, Ioannis ; Rafei-Shamsabadi, David Ali ; Bruckner-Tuderman, Leena ; Nyström, Alexander ; Kiritsi, Dimitra ; Dengjel, Jörn

In: Journal of Investigative Dermatology, 2020, vol. 140, no. 11, p. 2280-2290.e4

Chronic skin wounds accompany many prevalent age-related diseases and are a major cause of morbidity and mortality. Both keratinocytes and fibroblasts contribute to the pathomechanisms in chronic skin wounds. Dysregulated pathways in the epidermis have been extensively studied, but little is known of the influence of dermal fibroblasts on chronic wounding. We isolated fibroblasts from chronic...

Tissue engineering of skin: human tonsil-derived mesenchymal cells can function as dermal fibroblasts

Böttcher-Haberzeth, Sophie ; Biedermann, Thomas ; Klar, Agnieszka ; Pontiggia, Luca ; Rac, Jürgen ; Nadal, David ; Schiestl, Clemens ; Reichmann, Ernst ; Meuli, Martin

In: Pediatric Surgery International, 2014, vol. 30, no. 2, p. 213-222

Differential expression of granulocyte, macrophage, and hypoxia markers during early and late wound healing stages following transplantation of tissue-engineered skin substitutes of human origin

Klar, Agnieszka ; Böttcher-Haberzeth, Sophie ; Biedermann, Thomas ; Michalak, Katarzyna ; Kisiel, Marta ; Reichmann, Ernst ; Meuli, Martin

In: Pediatric Surgery International, 2014, vol. 30, no. 12, p. 1257-1264

Diet and longevity in the balance

Flatt, Thomas

In: Nature, 2009, vol. 462, no. 24, p. 989-990

Dietary restriction promotes longevity but impairs fecundity in many organisms. When the amino acids in a diet are fine-tuned, however, lifespan can be increased without loss of fecundity — at least in fruitflies.

Human amniotic fluid derived cells can competently substitute dermal fibroblasts in a tissue-engineered dermo-epidermal skin analog

Hartmann-Fritsch, Fabienne ; Hosper, Nynke ; Luginbühl, Joachim ; Biedermann, Thomas ; Reichmann, Ernst ; Meuli, Martin

In: Pediatric Surgery International, 2013, vol. 29, no. 1, p. 61-69

Rebuild, restore, reinnervate: do human tissue engineered dermo-epidermal skin analogs attract host nerve fibers for innervation?

Biedermann, Thomas ; Böttcher-Haberzeth, Sophie ; Klar, Agnieszka ; Pontiggia, Luca ; Schiestl, Clemens ; Meuli-Simmen, Claudia ; Reichmann, Ernst ; Meuli, Martin

In: Pediatric Surgery International, 2013, vol. 29, no. 1, p. 71-78

A new model for preclinical testing of dermal substitutes for human skin reconstruction

Hartmann-Fritsch, Fabienne ; Biedermann, Thomas ; Braziulis, Erik ; Meuli, Martin ; Reichmann, Ernst

In: Pediatric Surgery International, 2013, vol. 29, no. 5, p. 479-488

Matriderm® 1mm versus Integra® Single Layer 1.3mm for one-step closure of full thickness skin defects: a comparative experimental study in rats

Böttcher-Haberzeth, Sophie ; Biedermann, Thomas ; Schiestl, Clemens ; Hartmann-Fritsch, Fabienne ; Schneider, Jörg ; Reichmann, Ernst ; Meuli, Martin

In: Pediatric Surgery International, 2012, vol. 28, no. 2, p. 171-177

Skingineering I: engineering porcine dermo-epidermal skin analogues for autologous transplantation in a large animal model

Braziulis, Erik ; Biedermann, Thomas ; Hartmann-Fritsch, Fabienne ; Schiestl, Clemens ; Pontiggia, Luca ; Böttcher-Haberzeth, Sophie ; Reichmann, Ernst ; Meuli, Martin

In: Pediatric Surgery International, 2011, vol. 27, no. 3, p. 241-247

Characterization of Canine Dendritic Cells in Healthy, Atopic, and Non-allergic Inflamed Skin

Ricklin, Meret ; Roosje, Petra ; Summerfield, Artur

In: Journal of Clinical Immunology, 2010, vol. 30, no. 6, p. 845-854