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Host genetics of invasive Aspergillus and Candida infections

Wójtowicz, Agnieszka ; Bochud, Pierre-Yves

In: Seminars in Immunopathology, 2015, vol. 37, no. 2, p. 173-186

Effects of wheat-flour biscuits fortified with iron and EDTA, alone and in combination, on blood lead concentration, iron status, and cognition in children: a double-blind randomized controlled trial

Bouhouch, Raschida R. ; El-Fadeli, Sana ; Andersson, Maria ; Aboussad, Abdelmounaim ; Chabaa, Laila ; Zeder, Christophe ; Kippler, Maria ; Baumgartner, Jeannine ; Sedki, Azzedine ; Zimmermann, Michael B.

In: The American Journal of Clinical Nutrition, 2016, vol. 104, no. 5, p. 1318-1326

Different coordination abilities of 1,7- and 4,7-phenanthroline in the reactions with copper(II) salts: Structural characterization and biological evaluation of the reaction products

Stevanović, Nevena Lj. ; Andrejević, Tina P. ; Crochet, Aurélien ; Ilic-Tomic, Tatjana ; Drašković, Nenad S. ; Nikodinovic-Runic, Jasmina ; Fromm, Katharina M. ; Djuran, Miloš I. ; Glišić, Biljana Đ.

In: Polyhedron, 2019, vol. 173, p. 114112

The reactions between equimolar amounts of CuX2 (X = NO3− and CF3SO3−) and two aromatic nitrogen-containing heterocycles differing in the position of nitrogen atoms, 1,7- and 4,7-phenanthroline (1,7- and 4,7-phen), were performed in ethanol/methanol at room temperature. When CuX2 salts were mixed with 4,7-phen, two copper(II) complexes, [Cu(NO3)2(4,7-Hphen)2](NO3)2 (1) and...

Antigen-specific Th17 cells are primed by distinct and complementary dendritic cell subsets in oropharyngeal candidiasis

Trautwein-Weidner, Kerstin ; Gladiator, André ; Kirchner, Florian R. ; Becattini, Simone ; Rülicke, Thomas ; Sallusto, Federica ; LeibundGut-Landmann, Salomé

In: PLoS pathogens, 2015, vol. 11, no. 10, p. e1005164

Candida spp. can cause severe and chronic mucocutaneous and systemic infections in immunocompromised individuals. Protection from mucocutaneous candidiasis depends on T helper cells, in particular those secreting IL-17. The events regulating T cell activation and differentiation toward effector fates in response to fungal invasion in different tissues are poorly understood. Here we generated...

Silver(I) complexes with 4,7-phenanthroline efficient in rescuing the zebrafish embryos of lethal Candida albicans infection

Pavic, Aleksandar ; Savić, Nada D. ; Glišić, Biljana Đ. ; Crochet, Aurélien ; Vojnovic, Sandra ; Kurutos, Atanas ; Stanković, Dalibor M. ; Fromm, Katharina M. ; Nikodinovic-Runic, Jasmina ; Djuran, Miloš I.

In: Journal of Inorganic Biochemistry, 2019, vol. 195, p. 149–163

Five novel silver(I) complexes with 4,7-phenanthroline (4,7-phen), [Ag(NO3-O)(4,7- phen-μ-N4,N7)]n (1), [Ag(ClO4-О)(4,7-phen-μ-N4,N7)]n (2), [Ag(CF3COO-O)(4,7- phen-μ-N4,N7)]n (3), [Ag2(H2O)0.58(4,7-phen)3](SbF6)2 (4) and {[Ag2(H2O)(4,7- phen-μ-N4,N7)2](BF4)2}n (5) were synthesized, structurally elucidated and biologically evaluated. These complexes showed selectivity towards Candida spp....

Nutrient-Dependent Efficacy of the Antifungal Protein YvgO Correlates to Cellular Proliferation Rate in Candida albicans 3153A and Byssochlamys fulva H25

Manns, David ; Churey, John ; Worobo, Randy

In: Probiotics and Antimicrobial Proteins, 2014, vol. 6, no. 3-4, p. 198-207

Candida colonization index and subsequent infection in critically ill surgical patients: 20years later

Eggimann, Philippe ; Pittet, Didier

In: Intensive Care Medicine, 2014, vol. 40, no. 10, p. 1429-1448

Mononuclear silver(I) complexes with 1,7-phenanthroline as potent inhibitors of Candida growth

Savić, Nada D. ; Vojnovic, Sandra ; Glišić, Biljana Đ. ; Crochet, Aurélien ; Pavic, Aleksandar ; Janjić, Goran V. ; Pekmezović, Marina ; Opsenica, Igor M. ; Fromm, Katharina M. ; Nikodinovic-Runic, Jasmina ; Djuran, Miloš I.

In: European Journal of Medicinal Chemistry, 2018, vol. 156, p. 760–773

Mononuclear silver(I) complexes with 1,7-phenanthroline (1,7-phen), [Ag(NO3-O,O′) (1,7-phen-N7)2] (1) and [Ag(1,7-phen-N7)2]X, X = ClO4− (2), CF3SO3− (3), BF4− (4) and SbF6− (5) were synthesized and structurally characterized by NMR (1H and 13C), IR and UV–Vis spectroscopy and ESI mass spectrometry. The crystal structures of 1, 3 and 4 were determined by single-crystal X-ray...

Localization and functional characterization of the pathogenesis-related proteins Rbe1p and Rbt4p in Candida albicans

Bantel, Annick ; Darwiche, Rabih ; Rupp, Steffen ; Schneiter, Roger ; Sohn, Kai

In: PLOS ONE, 2018, vol. 13, no. 8, p. e0201932

Members of the Cysteine-rich secretory protein, Antigen 5 and Pathogenesis-related 1 (CAP) protein superfamily are important virulence factors in fungi but remain poorly characterized on molecular level. Here, we investigate the cellular localization and molecular function of Rbe1p and Rbt4p, two CAP family members from the human pathogen Candida albicans. We unexpectedly found that Rbe1p...

Invasive candidiasis: comparison of management choices by infectious disease and critical care specialists

Eggimann, Philippe ; Calandra, Thierry ; Fluckiger, Ursula ; Bille, Jacques ; Garbino, Jorge ; Glauser, Michel-Pierre ; Marchetti, Oscar ; Ruef, Christian ; Täuber, Martin ; Pittet, Didier

In: Intensive Care Medicine, 2005, vol. 31, no. 11, p. 1514-1521